Curcumins Membrane-Mediated Protection against the Monomeric, Fibrillar Oligomeric, and Non-fibrillar Oligomeric Forms of Amyloid Beta

CA Sallaberry - 2021 - search.proquest.com
Curcumin also has many neuroprotective properties in many … understand curcumin’s
membrane-mediated neuroprotection … that curcumin seems to provide evident membrane-mediated

Curcumin Reduces Amyloid Beta Oligomer Interactions with Anionic Membranes

CA Sallaberry, BJ Voss, WB Stone… - ACS Chemical …, 2023 - ACS Publications
Curcumin is a small polyphenolic molecule that provides an interesting opportunity to
understand the fundamental mechanisms of membrane-mediated … β-sheet formation and toxicity. …

Supplementation with Curcuma longa reverses neurotoxic and behavioral damage in models of Alzheimer's disease: a systematic review

IM da Costa, MA de Moura Freire… - Current …, 2019 - ingentaconnect.com
… The neuroprotective effect of curcumin is also possibly membrane-mediated, since its …
a decrease in the toxicity and formation of ROS due to the ability of curcumin in potentiating …

[HTML][HTML] Curcumin dictates divergent fates for the central salt bridges in amyloid-β40 and amyloid-β42

B Chandra, VS Mithu, D Bhowmik, AK Das, B Sahoo… - Biophysical …, 2017 - cell.com
… Both Zn 2+ and curcumin are known to interact with the toxic oligomers of Aβ 42 , and
sequester them by accelerating their precipitation, which yield similar nonfibrillar aggregates. …

[HTML][HTML] New promising therapeutic avenues of curcumin in brain diseases

T Benameur, G Giacomucci, MA Panaro, M Ruggiero… - Molecules, 2021 - mdpi.com
… The neuroprotective effect of curcumin, probably membrane-mediated, seems to act by
reducing toxicity induced by a wide range of Aβ conformers, including monomeric, oligomeric, pre…

Self-assembled curcumin–poly (carboxybetaine methacrylate) conjugates: potent nano-inhibitors against amyloid β-protein fibrillogenesis and cytotoxicity

G Zhao, X Dong, Y Sun - Langmuir, 2018 - ACS Publications
… It is seen that 5 and 10 μM curcumin presented little reduction of the toxicity of Aβ 42
aggregates (Figure 3c,d), and there was only 37% viability increase (from 51% to 70%) when …

[图书][B] Turmeric and curcumin for neurodegenerative diseases

M Obulesu - 2021 - books.google.com
… of metal chelators to overcome metal-induced toxicity. This is his third monograph with …
Curcumin-mediated neuroprotection against amyloid-β-induced mitochondrial dysfunction …

Research Mechanism and Progress of the Natural Compound Curcumin in Treating Alzheimer's Disease

L Li, F Wang, X Jia, L Yao, Y Liu - Mini Reviews in Medicinal …, 2024 - ingentaconnect.com
… and neuroprotective effects of curcumin on the HEK293 kidney cell line using
immunofluorescence. The impact of curcumin on … potential have a higher risk of increased toxicity. …

The mechanisms of action of curcumin in Alzheimer's disease

M Tang, C Taghibiglou - Journal of Alzheimer's disease, 2017 - content.iospress.com
… month [24], the neuroprotective role of curcumin in AD is a possibility… that curcumin protected
against Aβ membrane-mediatedcurcumin has the potential to modulate tau-induced toxicity

Potential Use of Curcuminoids for the Treatment of Alzheimer's Disease

T Ahmed, S Javed, A Tariq… - Neuroprotective Effects of …, 2017 - Wiley Online Library
Membranemediated neuroprotection by curcumin from amyloidβpeptideinduced toxicity.
Langmuir 2013; 29(37): 11713–11723. Lim GP, Chu T, Yang F, Beech W, Frautschy SA, …