Metabolic engineering of methanotrophic bacteria for industrial biomanufacturing

CA Henard, MT Guarnieri - Methane biocatalysis: paving the way to …, 2018 - Springer
… To this end, we are actively focused on improving transformation efficiencies in methanotrophic
bacteria by leveraging bacteriophage lambda red recombineering (Sharan et al. 2009; …

Prospects of microbial cell factories developed through systems metabolic engineering

M Gustavsson, SY Lee - Microbial Biotechnology, 2016 - Wiley Online Library
… yield, productivity and titre, and the cost effectiveness of … to develop an industrial strain
through metabolic engineeringefficient chemical production is the metabolic engineering of …

Oxidative fermentations and exopolysaccharides production by acetic acid bacteria: a mini review

S La China, G Zanichelli, L De Vero, M Gullo - Biotechnology letters, 2018 - Springer
… This procedure ensures low production costs, high performance and does not require …
Indeed, an increase of both production and tolerance to acetic acid was highlighted in a …

Holistic bioengineering: rewiring central metabolism for enhanced bioproduction

S Aslan, E Noor, A Bar-Even - Biochemical Journal, 2017 - portlandpress.com
Metabolic engineering of microbes now supports the … Successful engineering of a microbe
for the efficient bioproduction of a … of PKT in metabolic engineering was to enhance ethanol …

[HTML][HTML] Metabolic engineering using acetate as a promising building block for the production of bio‐based chemicals

G Gong, B Wu, L Liu, J Li, Q Zhu, M He, G Hu - Engineering Microbiology, 2022 - Elsevier
… of acetate as a building block in industrial biotechnology for the … Acetic acid bacteria
represent a group of strictly aerobic … thus increasing biochemicals productivity from acetate. This …

Biomanufacturing: history and perspective

YHP Zhang, J Sun, Y Ma - … Microbiology and Biotechnology, 2017 - academic.oup.com
… by genetic engineering, metabolic engineering, synthetic … adaptors to focus on process
efficiency, flexibility, manufacturing … However, new microbial cell factories improved by synthetic …

Engineering acetyl-CoA metabolic shortcut for eco-friendly production of polyketides triacetic acid lactone in Yarrowia lipolytica

H Liu, M Marsafari, F Wang, L Deng, P Xu - Metabolic Engineering, 2019 - Elsevier
… conversion efficiency and cost-efficiency. This work also highlights that low-cost acetic acid
could be … Here we explored two independent metabolic engineering strategies to improve the …

Metabolic engineering strategies toward production of biofuels

KR Choi, S Jiao, SY Lee - Current Opinion in Chemical Biology, 2020 - Elsevier
… with higher efficiencies. In this article, metabolic engineering strategies recently exploited
to … endogenous genes for spermidine biosynthesis to enhance acetic acid tolerance N/A [40] …

Tools and strategies of systems metabolic engineering for the development of microbial cell factories for chemical production

YS Ko, JW Kim, JA Lee, T Han, GB Kim… - Chemical Society …, 2020 - pubs.rsc.org
… biology and biotechnology, industrial biotechnology, and … , their performance needs to be
enhanced. This is where … target genes that confer improved tolerance to acetic acid were found. …

Metabolic engineering of Escherichia coli carrying the hybrid acetone-biosynthesis pathway for efficient acetone biosynthesis from acetate

H Yang, B Huang, N Lai, Y Gu, Z Li, Q Ye, H Wu - Microbial Cell Factories, 2019 - Springer
… for industrial biomanufacturing of acetone by engineered E. … A large proportion of acetic
acid are produced chemically by … to increase the productivity of acetone from acetate, using the …