Cigarette smoke promotes colorectal cancer through modulation of gut microbiota and related metabolites

X Bai, H Wei, W Liu, OO Coker, H Gou, C Liu, L Zhao… - Gut, 2022 - gut.bmj.com
Cigarette smoking is a major risk factor for colorectal cancer (CRC). We aimed to investigate
whether cigarette smoke … CRC by altering the gut microbiota and related metabolites. …

Pre-diagnostic circulating metabolites and colorectal cancer risk in the cancer prevention study-II nutrition cohort

ML McCullough, RA Hodge, PT Campbell, VL Stevens… - Metabolites, 2021 - mdpi.com
metabolites were associated with colorectal cancer risk at a false discovery rate < 0.20. These
metabolitesTobacco use is associated with lower bilirubin levels [14]; therefore, potential …

Alcohol consumption-related metabolites in relation to colorectal cancer and adenoma: two case-control studies using serum biomarkers

JR Troche, ST Mayne, ND Freedman, FM Shebl… - PLoS …, 2016 - journals.plos.org
… ), but no association for colorectal cancer. In conclusion, there … consumption-related
metabolites and colorectal cancer or … (Navy Colon Adenoma Study), sex, and tobacco use (never …

Circulating tryptophan metabolites and risk of colon cancer: results from case‐control and prospective cohort studies

N Papadimitriou, MJ Gunter, N Murphy… - … journal of cancer, 2021 - Wiley Online Library
… Established risk factors for colorectal cancer include obesity, diabetes, consumption of
alcohol, red and processed meats and tobacco smoking. Being physically active and consuming …

Cigarette smoking behaviour and blood metabolomics

F Gu, A Derkach, ND Freedman… - International journal …, 2016 - academic.oup.com
… associations between cigarette smoking and metabolites using an … colorectal cancer, which
included metabolomics profiles of baseline serum samples for 255 incident colorectal cancer

Association between metabolites and the risk of lung cancer: a systematic literature review and meta-analysis of observational studies

KB Lee, L Ang, WP Yau, WJ Seow - Metabolites, 2020 - mdpi.com
… Currently, lung cancer incidence and mortality rates are … to the lower prevalence of tobacco
smoking [6]. However, lung … on other cancers, such as colorectal cancer and gastric cancer, …

[HTML][HTML] Association of cigarette smoking with risk of colorectal cancer subtypes classified by gut microbiota

JA Cai, YZ Zhang, ED Yu, WQ Ding, ZS Li… - Tobacco Induced …, 2023 - ncbi.nlm.nih.gov
… SCFAs are one of the end-products of gut microbiota metabolism and play an important
role in lipid metabolism, energy homeostasis, regulation of the immune system, and …

Changes in lipids composition and metabolism in colorectal cancer: a review

A Pakiet, J Kobiela, P Stepnowski, T Sledzinski… - Lipids in health and …, 2019 - Springer
… In this review paper, we discuss lipid alterations associated with colorectal cancer (CRC),
with special emphasis on fatty acids (FAs) and their potential therapeutic and diagnostic …

Metabolomics profiles of smokers from two ethnic groups with differing lung cancer risk

R Dator, PW Villalta, N Thomson, J Jensen… - Chemical research in …, 2020 - ACS Publications
… and their associated metabolites in populations with differing lung cancer risk as in African
… to the detrimental effects of tobacco use among smokers. Understanding the differences in …

Diet, microorganisms and their metabolites, and colon cancer

SJD O'keefe - Nature reviews Gastroenterology & hepatology, 2016 - nature.com
… /or carcinogenic metabolites, which increase the risk of neoplastic progression… metabolite
effects, which could be modified by diet to achieve the objective of preventing colorectal cancer