Role of metals in Alzheimer's disease

N Das, J Raymick, S Sarkar - Metabolic brain disease, 2021 - Springer
… use of metal chelating agents may be a viable method for ameliorating Alzheimers Disease
pathology, as its etiology remains obscure. We conclude that, although metal therapies can …

[HTML][HTML] Metals in Alzheimer's disease

M Babić Leko, L Langer Horvat, E Španić Popovački… - Biomedicines, 2023 - mdpi.com
… The role of metals in the pathogenesis of Alzheimers disease (AD) is still debated. Although
… changes in essential metal homeostasis and exposure to environmental heavy metals to the …

[HTML][HTML] Metals and Alzheimer's disease: how far have we come in the clinic?

PA Adlard, AI Bush - Journal of Alzheimer's Disease, 2018 - content.iospress.com
… “Metals and Alzheimers disease” [1], in which we reviewed the current literature around the
mechanisms by which metal ions interacted with key Alzheimers disease … accelerate disease

Heavy metals exposure and Alzheimer's disease and related dementias

KM Bakulski, YA Seo, RC Hickman… - … of Alzheimer's …, 2020 - content.iospress.com
… Manganese is an essential trace metal required for normal … Understanding the roles of these
heavy metals in the etiology of … metals in this review because neurotoxicity of these metals is …

Metals and neuronal metal binding proteins implicated in Alzheimer's disease

JS Cristóvão, R Santos… - Oxidative medicine and …, 2016 - Wiley Online Library
… In agreement with a role of metal ions in pathology, molecules designed to chelate Zn 2+ …
-metal cross talks in neurodegeneration, we undertake an overview of proteins with metal

The role of trace metals in Alzheimer's disease

CA De Benedictis, A Vilella, A Grabrucker - 2019 - researchrepository.ul.ie
… of Alzheimers disease (AD). Both Aβ and tau are metal-binding proteins. Essential trace …
Herein we provide an overview of metals and metal-binding proteins and their pathophysi…

[HTML][HTML] Common and trace metals in Alzheimer's and Parkinson's diseases

J Doroszkiewicz, JA Farhan, J Mroczko… - International Journal of …, 2023 - mdpi.com
… Trace elements and metals play critical roles in the normal … such as Alzheimers disease
(AD) and Parkinson’s disease (PD). In a … Toxic metals, like lead and cadmium, impair synaptic …

Metal ions in Alzheimer's disease: a key role or not?

Y Liu, M Nguyen, A Robert… - Accounts of chemical …, 2019 - ACS Publications
… of redox metals in biology (biomimetic oxidations, mechanism of action of peroxide based
antimalarial drugs) and redox metal homeostasis for chemotherapy of Alzheimers disease. …

[HTML][HTML] Current understanding of metal ions in the pathogenesis of Alzheimer's disease

L Wang, YL Yin, XZ Liu, P Shen, YG Zheng… - Translational …, 2020 - Springer
… The homeostasis of metal ions, such as iron, copper, zinc and calcium, in the brain is crucial
metal ions in the brain is closely related to the onset and progression of Alzheimers disease

Molecular mechanisms of metal toxicity in the pathogenesis of Alzheimer's disease

MT Kabir, MS Uddin, S Zaman, Y Begum… - Molecular …, 2021 - Springer
… mentioned metal imbalance in … metals, but rather to a more initial distribution of intracellular
ions in an unclear manner. Therefore, brain metal homeostasis is regulated by several metal