… pathways whereby metformin ameliorated inflammation and … the polarization of macrophages
to the M2 phenotype. … did not detect whether metformin activates AMPK in the adipose …

… , metformin reduced the body weight and hepatic steatosis of the HFD‑induced obese mice,
without altering … link between adipose tissue phenotype and autophagy, which is altered by …

… -term metformin treatment reversed lipid accumulation in liver by central and peripheral
oxidation, improved the glucose homeostasis, ameliorated the inflammation in adipose tissue …

… fatty phenotype in the animals studied, and the difference in the pharmacokinetics of metformin
… fed with a diet promoting the development of a fatty liver. These models generate uniform …

… plus MOR ameliorates weight gain induced by HFD without … Considering the heterogeneity
of macrophage phenotypes in … on switching of macrophage phenotype, we concentrated on …

… of lipid metabolism, chronic inflammation and fatty liver disease [32]… of inflammation in hepatic
tissue, non-alcohoic fatty liver disease (… Metformin treatment significantly ameliorated such …

… role of SIRT1 in the metformin-improved fatty liver and the … In this study, we also confirmed
that metformin ameliorated HFD-… In addition, dynamic observation of macrophage phenotype …

… Whilst lifestyle modification may ameliorate liver fat, it is often … They found no change in fasting
hepatic fatty acid … of the diversity in participant phenotype across studies, factors including …

… Furthermore, combination of MET and GEN ameliorates liver inflammation by switching
macrophage into M2 phenotype, decreasing macrophage infiltration, reducing expression of pro-…

… overall metaboinflammatory phenotypes irrespective of … /inflammatory parameters we
measured. Lastly, we note that the extent to which metformin ameliorated HFD-induced adiposity …