Protective effects of melatonin on methamphetamine-induced blood–brain barrier dysfunction in rat model
J Namyen, K Permpoonputtana, C Nopparat… - Neurotoxicity …, 2020 - Springer
… The results showed a significantly increased hippocampal expression of albumin (P < 0.05;
Fig. 1(m)) induced by METH as compared to control groups. This effect could be protected by …
Fig. 1(m)) induced by METH as compared to control groups. This effect could be protected by …
Extended-access methamphetamine self-administration elicits neuroinflammatory response along with blood-brain barrier breakdown
… Specifically, there was an increase of BBB permeability due to alterations … brain regions
analyzed, we concluded that METH abuse leads to hippocampal and striatal barrier permeability …
analyzed, we concluded that METH abuse leads to hippocampal and striatal barrier permeability …
Peripheral ammonia and blood brain barrier structure and function after methamphetamine
NA Northrop, LE Halpin, BK Yamamoto - Neuropharmacology, 2016 - Elsevier
… Methamphetamine (Meth) is a widely abused psychostimulant known to damage brain …
Similar effects were observed in various regions of the cortex as well as the hippocampus …
Similar effects were observed in various regions of the cortex as well as the hippocampus …
[HTML][HTML] Endoplasmic reticulum stress mediates methamphetamine-induced blood–brain barrier damage
X Qie, D Wen, H Guo, G Xu, S Liu, Q Shen… - Frontiers in …, 2017 - frontiersin.org
… Methamphetamine (METH) abuse causes serious health problems worldwide, and long-term
use of METH disrupts the blood–brain barrier (BBB). Herein, we explored the potential …
use of METH disrupts the blood–brain barrier (BBB). Herein, we explored the potential …
Methamphetamine and the Blood–Brain Barrier
RA Leitão, V Coelho-Santos, AP Silva - Neuropathology of drug addictions …, 2016 - Elsevier
… overlooked, we showed that METH (30 mg/kg, ip) increased BBB permeability in the mice
hippocampus together with an increase of MMP-9 activity and immunoreactivity (Martins et al., …
hippocampus together with an increase of MMP-9 activity and immunoreactivity (Martins et al., …
[HTML][HTML] Overview of blood-brain barrier dysfunction in methamphetamine abuse
L Pang, Y Wang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
… This study demonstrated that chronic METH increased α-syn expression in mice hippocampal
neurons [68]. The α-syn produced by neurons were spread to astrocytes and gradually …
neurons [68]. The α-syn produced by neurons were spread to astrocytes and gradually …
[HTML][HTML] Silencing microRNA-143 protects the integrity of the blood-brain barrier: implications for methamphetamine abuse
Y Bai, Y Zhang, J Hua, X Yang, X Zhang, M Duan… - Scientific reports, 2016 - nature.com
… TJP expression induced by methamphetamine in the cortex (d) and hippocampus (e), as …
Methamphetamine treatment transiently increased the phosphorylation of ERK, JNK and …
Methamphetamine treatment transiently increased the phosphorylation of ERK, JNK and …
[HTML][HTML] The psychoactive drug of abuse mephedrone differentially disrupts blood-brain barrier properties
TP Buzhdygan, CR Rodrigues, HM McGary… - Journal of …, 2021 - Springer
… Methamphetamine, which closely resembles chemical structure and pharmacological …
Here, we report that extracellular PECAM-1 was transiently increased in hBMVEC at 2 h after …
Here, we report that extracellular PECAM-1 was transiently increased in hBMVEC at 2 h after …
Effects of HIV-1 Tat and Methamphetamine on Blood-Brain Barrier Integrity and Function In Vitro
S Patel, CR Leibrand, P Palasuberniam… - Antimicrobial agents …, 2017 - Am Soc Microbiol
… [of body weight]) methamphetamine exposure in mice, barrier permeability to the paracellular
compound Evans blue was altered, albeit transiently, with increases observed at 24 h but …
compound Evans blue was altered, albeit transiently, with increases observed at 24 h but …
Impact of Methamphetamine on Blood-Brain Barrier: Role of Exercice
VCA Pinheiro - 2016 - search.proquest.com
… Since our results suggest an increase of the BBB permeability in the hippocampus, it may
present an opportunity to enhance delivery of chemotherapeutic agents to the underlying …
present an opportunity to enhance delivery of chemotherapeutic agents to the underlying …