… CSE −/− mice without CS exposure showed higher cytokine and chemokine levels, and this
… In conclusion, in murine acute-on-chronic pulmonary disease, CSE knockout aggravated …

… Hamelet J, Maurin N, Fulchiron R, Delabar JM, Janel N: Mice lacking cystathionine beta
synthase have lung fibrosis and air space enlargement. Exp Mol Pathol 2007; 83:249-253. …

… Additionally, we revealed that fibroblast growth factor-2 (FGF-2) increases intracellular RSS
… functions by growth factors/cytokines via the induction of specific RSS-producing enzymes. …

… While suppression of PGRMC1 expression inhibits cancer growth as described above,
mechanisms by which PGRMC1 facilitates cancer growth has not fully been examined. We …

… Unlike the majority of vital organs, the lung is directly open to the air and constantly exposed
to pathogens, allergens, irritants, and toxins; thus, in general, the lung has a high risk of …

… in the lung is progressive and irreversible pulmonary fibrosis, … Although PQ-induced pulmonary
fibrosis is the leading … , CBS-deficient mice have lung fibrosis and air space enlargement (…

… −/− mice manifested fibrotic injuries and air space enlargement in the lungs, with increased
… most for up to 5 weeks after birth with severe growth retardation (225). However, Hamelet et …

… H 2 S concentrations and survival was assessed in septic patients with lung infection. … mice
with a constitutive knock-out of cystathionine-γ lyase (Cse) gene (Cse -/- ) and wild-type mice …

… lungs and in chronic lung diseases, including chronic obstructive pulmonary disease (COPD),
idiopathic pulmonary fibrosis (… growth in the lung significantly increased in Cars2 +/− mice …

Introduction: Homocystinuria due to cystathionine β-synthase (CBS) deficiency, the most
frequent inborn error of sulfur amino acid metabolism, is characterized biochemically by …