… This article is part of a Special Issue entitled: Cytochrome P450 biodiversity and biotechnology,
… limited areas of plants, animals, fungi and bacteria to see how the quest is coming along. …

… The cytochromes P450 (P450s or CYPs) are an enzyme superfamily, members of which …
archaea and bacteria through to man [1 • ]. The majority of P450 enzymes are monooxygenases…

… in SMC that originate from NCBI RefSeq genomes and that are … should augment our
knowledge on the structural diversity of RiPPs and the biochemical reactions that cytochromes P450 …

… P450cam (CYP101A1) is a model example of a bacterial Class I P450, first discovered in …
and bacterial and fungal origins make them prime candidates for biotechnological applications. …

… somewhat surprising, as this was not the case for bacteria and … Microbial cytochromes
P450: Biodiversity and biotechnology. Where do cytochromes P450 come from, what do they do …

… In bacteria, CYPs are involved in processes such … Bacterial CYPs are generally soluble
enzymes, thus are convenient for structural and functional studies. This led to the use of bacterial …

… However, while CYPs are often harbored by microorganisms … in this study may have come
more likely from human sources … annotated for functions of biotechnological interest with the …

… biotechnological applications of secondary metabolites produced mostly by Bacillus species
(Table 1), comprehensive analysis of cytochrome P450 … world come from these species 54 . …

… reactions are catalyzed by the cytochrome P450 … are carried out by different microorganisms,
given in italics above the transformation arrow. The specific molecular transformations are …

… Kelly, SL; Kelly, DE Microbial cytochromes P450: Biodiversity and biotechnology. Where
do cytochromes P450 come from, what do they do and what can they do for us? Philos. Trans. …