Polymer-coated cardiopulmonary bypass circuit attenuates upregulation of both proteases/protease inhibitors and platelet degranulation in pigs

S Suehiro, K Shimizu, K Imai, A Niii, K Akeho… - …, 2017 - journals.sagepub.com
… However, aprotinin has subsequently been licensed for use in coronary artery bypass surgery.
Because the rapid activation of the defense systems (serine protease) occurs immediately …

The inflammatory response to extracorporeal membrane oxygenation (ECMO): a review of the pathophysiology

JE Millar, JP Fanning, CI McDonald, DF McAuley… - Critical care, 2016 - Springer
… and targeting the inflammatory response to cardiopulmonary bypass (CPB) [36… an association
between the lowest haematocrit recorded during CPB and … Coronary artery bypass grafting

Retrospective evaluation of ultrafiltration during cardiac surgery with cardiopulmonary bypass in adult patients with increased neutrophil to lymphocyte ratio

Ş Şahinalp, K Çeviker, M tolga SOYAL… - Journal of Surgery and …, 2020 - dergipark.org.tr
attenuate whole body inflammatory response after CPB in adult … activation, release of cytokines,
leukocyte activation along with … of neutrophil:lymphocyte ratios following coronary artery

Effects of Sodium-Glucose Transporter 2 Inhibitors (SGLT2-I) in Patients With Ischemic Heart Disease (IHD) Treated by Coronary Artery Bypass Grafting via MiECC …

C Sardu, M Massetti, N Testa, LD Martino… - Frontiers in …, 2021 - frontiersin.org
… had the lowest values of IL-1, IL-6, and TNF-α (p < 0.05). At one year of follow-up, SGLT2-I
users vs non-T2DM and non-SGLT2-I users vs non-T2DM users had a higher rate of all deaths…

Does heart surgery change the capacity of α1-antitrypsin to inhibit the ATP-induced release of monocytic interleukin-1β? A preliminary study

A Agne, K Richter, S Tumpara, AL Sauer… - International …, 2020 - Elsevier
… We conclude that surgery involving cardiopulmonary bypass … during heart surgery is suited
to attenuate postoperative … , such as minimal-invasive coronary revascularization, minimized …

Evaluation of inflammation caused by cardiopulmonary bypass in a small animal model

Y Fujii - Biology, 2020 - mdpi.com
… 2 insufflation would attenuate the systemic inflammation with a reduction of cytokine levels,
… More recently, minimally invasive cardiac surgery and minimally invasive extracorporeal …

Postoperative complications associated with coronary artery bypass graft surgery and their therapeutic interventions

A Pooria, A Pourya, A Gheini - Future Cardiology, 2020 - Future Medicine
Cytokine and other chemical mediators from these pathways … ones with cardiopulmonary
bypass surgery duration longer … Minimally invasive CABG has better outcomes, in variant with …

Targeting of cell-free DNA by DNase I diminishes endothelial dysfunction and inflammation in a rat model of cardiopulmonary bypass

C Weber, A Jenke, V Chobanova, M Yazdanyar… - Scientific reports, 2019 - nature.com
… reflects endothelial function, was lowest in control animals and … to attenuate postoperative
cytokine release including anti-… trigger neutrophil activation and consequently the release of …

Efficacy of parasternal block to decrease intraoperative opioid use in coronary artery bypass surgery via sternotomy: a randomized controlled trial

S Bloc, BP Perot, H Gibert, JDL Koune… - Regional Anesthesia & …, 2021 - rapm.bmj.com
… to be maintained in patients (minimum patient state index was 11.7… techniques using
cardiopulmonary bypass (CPB) circuit. … sevoflurane if necessary, to attenuate the increase in BP …

Cardiopulmonary bypass with low-versus high-priming volume: comparison of inflammatory responses in a rat model

Y Fujii, M Shirai, Y Takewa, E Tatsumi - ASAIO Journal, 2016 - journals.lww.com
… with blood would attenuate systemic inflammatory responses … procedures, such as coronary
artery bypass grafting or single-… should be minimal to ensure the safe application of minimal