… of massively parallel sequencing (MPS) in heteroplasmy detection. I present here some critical
issues that should be considered in heteroplasmy … reveal new insights into the molecular …

… sequenced by massive parallel sequencing (MPS). As a consequence, the sequencing …
Other than an unbiased amplification of whole genome, there were 13 new heteroplasmies …

… is increasing in not only forensic science and classical clinical medicine,37 but also developing
areas of laboratory medicine2 and biotechnology.Fortunately, new programs like mDS …

… heteroplasmy and have revealed that mitochondrial DNA … propagation which is followed by
massive parallel sequencing [30,31… new mtDNA mutations that occur in heteroplasmy [64,65]. …

… , massively parallel sequencing (MPS) technologies have matured in step with cost reductions,
which provides a powerful tool for studying mtDNA … of mtDNA heteroplasmy and mutation, …

… mtDNA sequence, ii) assessing heteroplasmy for single point mutations with high accuracy,
and iii) detecting break positions and heteroplasmy … points and showed that a new PCR-free …

… Taking into account all the results mentioned above, the new strategy presented in the
present work based on the Nextera XT and MiSeq platform technology implementation, leads to …

… heteroplasmy (PHP) and length heteroplasmy (LHP) is limited. The application of massively
parallel sequencing in mtDNA … The ForenSeq mtDNA Whole Genome Kit, which contains a …

… 1977 and evolving into the next generation sequencing (NGS… DNA is not present, mitochondrial
DNA can be sequenced … for the presence of heteroplasmy (mutations in the mtDNA) and …

… The emergence of massively parallel sequencing (MPS) … of low-frequency changes in mtDNA
as new molecular markers. … at different positions of mitochondrial genome leads to unique …