Effect of acute mitochondrial dysfunction on hyperexcitable network activity in rat hippocampus in vitro
M Andreasen, S Nedergaard - Brain Research, 2021 - Elsevier
… Ca 2+ , mitochondrial ATP synthesis and reactive oxygen species (ROS) production (Brookes
et al.… We first tested whether tempol by itself could affect network excitability under baseline …
et al.… We first tested whether tempol by itself could affect network excitability under baseline …
Crosstalk between calcium and reactive oxygen species signaling in cancer
… cell surface and intracellular organelles, including the endoplasmic reticulum and mitochondria
… In turn, Ca 2+ signaling can influence the cellular generation of ROS, from sources such …
… In turn, Ca 2+ signaling can influence the cellular generation of ROS, from sources such …
Emerging perspectives on mitochondrial dysfunctioning and inflammation in epileptogenesis
S Singh, TG Singh - Inflammation Research, 2021 - Springer
… The increased mitochondrial reactive oxygen species (ROS) … give rise to the neuronal
excitability and neurodegeneration seen … Pharmacological modulation or manipulation of miRNAs …
excitability and neurodegeneration seen … Pharmacological modulation or manipulation of miRNAs …
[HTML][HTML] The complex interplay between mitochondria, ROS and entire cellular metabolism
AV Kuznetsov, R Margreiter, MJ Ausserlechner… - Antioxidants, 2022 - mdpi.com
… The mitochondrial respiration coupled with the electron transfer through the electron
transport chain are a major source of reactive oxygen species (ROS) production (see below). …
transport chain are a major source of reactive oxygen species (ROS) production (see below). …
[HTML][HTML] Reactive oxygen species: beyond their reactive behavior
A Tauffenberger, PJ Magistretti - Neurochemical Research, 2021 - Springer
… energy supporting cell growth and homeostasis. However, the dark side of energy production
is the formation of reactive oxygen species (ROS) as a by-product by the mitochondria’s …
is the formation of reactive oxygen species (ROS) as a by-product by the mitochondria’s …
Small conductance Ca2+-activated K+ channels in the plasma membrane, mitochondria and the ER: Pharmacology and implications in neuronal diseases
B Honrath, IE Krabbendam, C Culmsee… - Neurochemistry …, 2017 - Elsevier
… channels on neuronal excitability, neuronal dysfunction … of reactive oxygen species (ROS).
Further, a study in neutrophils revealed an effect of SK channel modulation on mitochondrial …
Further, a study in neutrophils revealed an effect of SK channel modulation on mitochondrial …
The machineries, regulation and cellular functions of mitochondrial calcium
… mechanism in neurons and other excitable cells), whereby Ca 2… , the MCU can be targeted
by reactive oxygen species (ROS), … in the modulation of SOCE, as previously suggested 119 . …
by reactive oxygen species (ROS), … in the modulation of SOCE, as previously suggested 119 . …
Changes in motor function and brain cortex mitochondrial active oxygen species production in aged mice
S Lores-Arnaiz, P Lombardi, AG Karadayian… - Experimental …, 2019 - Elsevier
… mitochondrial reactive oxygen species and the cumulative oxidative damage of mitochondrial
… Partial uncoupling by UCP-2 activity participates in the modulation of oxygen free radical …
… Partial uncoupling by UCP-2 activity participates in the modulation of oxygen free radical …
Mitochondrial Ca2+-activated K+ channels and their role in cell life and death pathways
… production via oxidative phosphorylation (OXPHOS), regulation of calcium (Ca 2+ ) homeostasis,
reactive oxygen species … have induced the observed protection by modulation of Ca 2+ …
reactive oxygen species … have induced the observed protection by modulation of Ca 2+ …
Impaired mitochondrial network excitability in failing guinea-pig cardiomyocytes
KY Goh, J Qu, H Hong, T Liu, LJ Dell'Italia… - Cardiovascular …, 2016 - academic.oup.com
… Studies in guinea-pig cardiomyocytes show that reactive oxygen species (ROS) produced
by a few mitochondria can propagate to their neighbours, triggering synchronized, cell-wide …
by a few mitochondria can propagate to their neighbours, triggering synchronized, cell-wide …