[PDF][PDF] Qualitative and Semi-Quantitative Analysis of Signal Transduction Networks

R Samaga - 2018 - pure.mpg.de
… to cellular signaling networks include the identification of signaling pathways and feedback
loops, and the analysis … different modeling methods that are central to this work (Section 2.4). …

Qualitative and semi quantitative systems approaches to complex systems modelling–Intuitive and flexible models of biological systems: A thesis submitted in partial …

M Alsharaiah - 2018 - researcharchive.lincoln.ac.nz
… in ways that produce nonlinear and complex systems behaviour such as oscillations. A number
of modelling approaches … components, while discrete models can simulate the biological …

Efficient parameter estimation for ODE models of cellular processes using semi-quantitative data

D Dorešić, S Grein, J Hasenauer - Bioinformatics, 2024 - academic.oup.com
… (ODE) models are used for a broad spectrum of applications, ranging from cellular signaling, …
To evaluate how well the three modeling approaches can recover the true measurement …

Semi-quantitative modelling of gene regulatory processes with unknown parameter values using fuzzy logic and Petri nets

J Bordon, M Moškon, N Zimic… - Fundamenta …, 2018 - content.iospress.com
… a semi-quantitative fuzzy model of each biological process [16], which enables us to model
system… cal interface for both qualitative and quantitative modelling approaches. On one hand, …

Model calibration and uncertainty analysis in signaling networks

T Heinemann, A Raue - Current opinion in biotechnology, 2016 - Elsevier
modeling cellular signal transduction networks has been the inference of crucial pathway
components and the qualitative … The spectrum of modeling approaches for signaling networks

Logical versus kinetic modeling of biological networks: applications in cancer research

L Calzone, E Barillot, A Zinovyev - Current Opinion in Chemical …, 2018 - Elsevier
… In this short review, we remind the reader how these two … of semi-quantitative approaches
for modeling large biological … , a number of qualitative modeling methods emerged in the …

Using both qualitative and quantitative data in parameter identification for systems biology models

ED Mitra, R Dias, RG Posner, WS Hlavacek - Nature communications, 2018 - nature.com
… to identify model parameters, but experimentalists are reluctant to acquire time courses,
which are more costly than qualitative or semi-quantitative measurements. Our approach allows …

Modelling signalling networks from perturbation data

M Dorel, B Klinger, T Gross, A Sieber… - …, 2018 - academic.oup.com
Intracellular signalling is realized by complex signalling … Modular Response Analysis (MRA)
is a convenient modelling method to study signalling networks in various contexts. …

[HTML][HTML] Formal derivation of qualitative dynamical models from biochemical networks

W Abou-Jaoudé, D Thieffry, J Feret - Biosystems, 2016 - Elsevier
… according to the relative position of some expressions that depend on the initial
concentrations of some proteins and on the rates of the reactions, with respect to some semi-quantitative

Signaling Networks. Simulations of Biochemical Interactions. Applications to Molecular Oncology

L Tortolina, N Castagnino, R Montagna… - Functional …, 2019 - taylorfrancis.com
Qualitative expectations become progressively more untractable for the direct intuition of …
semi-quantitative predictions are impossible. On the other end, the quantitative/semiquantitative