Evidence-based treatment for opioid use disorders: A national study of methadone dose levels, 2011–2017

T D'Aunno, SE Park, HA Pollack - Journal of substance abuse treatment, 2019 - Elsevier
… Consistent with earlier papers, we define an MMT program as a physical facility with resources
dedicated to treating opiate use disorders primarily through methadone. In 2017, 84% of …

Evaluation of QTc interval prolongation among patients with cancer using enteral methadone

AG Lovell, BMC Protus, ML Saphire… - American Journal of …, 2019 - journals.sagepub.com
… The primary outcome was the incidence of QTc prolongation on the study ECG in patients
taking low-dose, moderate-dose, and high-dose methadone. Secondary outcomes included …

Effective drug therapy for cocaine dependence: a milestone

KM Dürsteler, M Vogel - The Lancet, 2016 - thelancet.com
… , so the findings of the present study cannot be generalised to other TAVR devices. …
Moderate- vs high-dose methadone in the treatment of opioid dependence: a randomized trial

Buprenorphine & methadone dosing strategies to reduce risk of relapse in the treatment of opioid use disorder

KE Rudolph, NT Williams, ATS Goodwin… - … alcohol dependence, 2022 - Elsevier
… large randomized trials for OUD treatment that were part of the NIDA Clinical Trials Network
(… (2018) (we exclude the extended release naltrexone arm of this trial). Data was discretized …

Higher methadone dose at time of release from prison predicts linkage to maintenance treatment for people with HIV and opioid use disorder transitioning to the …

A Ahmad, DJ Bromberg, R Shrestha… - International Journal of …, 2024 - Elsevier
… From 2010 to 2014, men with HIV (N = 212) and opioid dependence before incarceration
were … As a prospective trial, allocation to MMT was at random and later by preference design (…

Dosing inequities in opioid use disorder treatment trials

DM Schiff, N Nidey, MJN Tiako - JAMA network open, 2024 - jamanetwork.com
opioid dependence, with a primary outcome of abstinence from nonprescribed opioids. Of
… in both the buprenorphine and methadone groups, similar to an earlier trial within the CTN …

Review of medication-assisted treatment for opioid use disorder

N Ghanem, D Dromgoole, A Hussein… - Journal of Osteopathic …, 2022 - degruyter.com
Randomized trials have shown that patients demonstrate … drive, relapse with high-dose
opioids may result in accidental … effects of methadone in the treatment of opioid dependence. Ann …

Polydrug abuse among opioid maintenance treatment patients is related to inadequate dose of maintenance treatment medicine

PK Heikman, LH Muhonen, IA Ojanperä - BMC psychiatry, 2017 - Springer
methadone in this study is at the recommended level (60 – 100 mg) according to reported
fixed high-dose … with more severe opioid dependence were started with methadone. In addition…

A preliminary investigation of the acute effects of delta-9-tetrahydrocannabinol on pain and opioid attentional bias among persons with opioid use disorder

NR Wolkowicz, M Sofuoglu, B Pittman… - Journal of Psychiatric …, 2024 - Elsevier
… pain processes in individuals receiving methadone treatment for OUD. More work … opioid
cues among participants receiving high-dose methadone, and decreased AB stability for opioid

Variation in opioid agonist dosing in clinical trials by race and ethnicity

RK Ross, S Inose, M Shulman, EV Nunes… - JAMA Network …, 2024 - jamanetwork.com
… were randomized to and initiated methadone (START) or buprenorphine (all 3 trials) treatment
from 3 trials (the methadone data were obtained from only 1 trial). To examine variation by …