CEA vaccines

A Bhagat, HK Lyerly, MA Morse… - Human Vaccines & …, 2023 - Taylor & Francis
immune response to tumor associated CEA without inducing … a Tat-CEA fusion protein also
led to preventative anti-tumor … -mediated responses compared to non-modified CEA plasmid …

mRNA: a versatile molecule for cancer vaccines

M Diken, LM Kranz, S Kreiter, U Sahin - Current Issues in Molecular …, 2017 - mdpi.com
… a personalized mRNA vaccine for induction of immune responses. … Modification of CEA
with both CRT and TAT PTD induces potent anti-tumor immune responses in RNA-pulsed DC

Protein transduction domain-mediated influenza NP subunit vaccine generates a potent immune response and protection against influenza virus in mice

Y Yin, BB Li, L Zhou, J Luo, X Liu, S Wang… - Emerging Microbes & …, 2020 - Taylor & Francis
… It is reported that the protein transduction domain (PTD) TATimmune response induced
by TAT-NP in intranasally … spleen cell suspensions two weeks after the last vaccination. The …

mRNA cancer vaccines—messages that prevail

C Grunwitz, LM Kranz - Cancer Vaccines, 2017 - Springer
… and quantity of the desired immune response. This review … Induction of relevant immune
responses in response to … nasal epithelium through rational modification of particle properties …

Dendritic cell vaccines for cancer therapy: fundamentals and clinical trials

GG Romagnoli, R Kaneno - … Bench to Bedside Immunotherapy of Cancers, 2021 - Springer
… and regulation of the immune system [9, 10], being usually … that administration of RNA-pulsed
DC was able to induce a … showed an ability to induce specific T response to CEA [146]. …

Biomaterials‐Based Vaccinatio in Cancer Therapy

R Sharma, R Malviya, S Sundram - Integration of Biomaterials …, 2023 - Wiley Online Library
… Antigen-induced immune responses are those that are … the vaccination had improved CD4
and CD8 responses to CEA, … , S., Therapeutic anti-tumor immunity triggered by injections of …

[PDF][PDF] Expression Mechanism of Immunogenic Cell Death-Related Molecules in Colorectal Cancer

R Zhang - J Gstro Hepato - jajgastrohepto.org
… can function as a tumor vaccine, killing not only cells induced … eliciting tumor-specific immune
responses against live tumor … induce ICD and trigger the body’s anti-tumor immunity is an …

[PDF][PDF] Ovarian cancer treatment with a liposome formulated mRNA vaccine in combination with (neo-) adjuvant chemotherapy: Study protocol of the OLIVIA phase I …

ST Paijens, AKL Reyners, M de Bruyn… - Tumor immunology and … - research.rug.nl
… the induction of a vaccine specific systemic immune response, … Modification of CEA with
both CRT and TAT PTD induces potent anti-tumor immune responses in RNA-pulsed DC

[PDF][PDF] mRNA-based therapeutics to induce immunity against cancer and infectious diseases

L Van Hoecke - 2020 - biblio.ugent.be
induction of antigen-specific immune responses by lipid-based delivery of mRNA vaccines.
… In summary, the chemical modification of nucleotides in IVT mRNA is an important …

Cell type preference of a novel human derived cell-permeable peptide dNP2 and TAT in murine splenic immune cells

S Lim, J Lee, JH Koo, TG Kang, SJ Ha, JM Choi - PloS one, 2016 - journals.plos.org
… is appropriate target for DC vaccination using cell-penetrating … potent target cell type for
modulating the immune system … could modulated OVA-induced allergic T cell responses in vivo …