… the molecular fingerprints of pancreatic NETs and the spectrum of tumoral heterogeneity. We
… of tumoral subclones between primary pancreatic NETs and metastatic sites. B. Temporal …

… show the heterogeneity of PanNENs, revealing key molecular events that … neuroendocrine
tumors. A case report demonstrated a liver metastasis refractory NET of an unknown primary …

… found and the degree of intratumoral heterogeneity of CNVs corresponded to SNV analysis.
… primary and metastatic lesions show a highly varying degree of intratumoral heterogeneity. …

… PNETs is due to mass-related burden of the primary tumor or metastatic … of this molecular
landscape have identified significant heterogeneity in the mutational profiles of non-functional …

… Neuroendocrine tumors (NETs) comprise a complex and highly heterogeneous group of
neoplasms that can arise all over the body, originating from neuroendocrine cells. NETs are …

… and clinically heterogeneous group of pancreatic neoplasms … ongoing clinical trial at the BC
Cancer Agency (clinicaltrials.gov … the molecular landscapes of these metastatic samples, to …

… We analyzed the MSK-MET cohort, comprising 189 patients with metastatic pancreatic
neuroendocrine tumors, to validate and perform survival analysis. Given the functional relevance …

… (WHO) grade is the best current tool to predict metastasis 7,8 . Insulinomas resemble normal
… ALT + tumors were identified by telomere length heterogeneity and the presence of large, …

… entity, and approximately half of the patients harbored liver metastasis when initially …
features of pancreatic neuroendocrine tumor, but the genetic alterations in the metastatic cases …

… We identified subpopulations of functional heterogeneity within malignant cells, immune cells,
and … Therefore, we sought to identify characteristics of primary tumor cells with metastatic …