… The peroxisome’s role as a redox mediator becomes especially evident during H 2 O 2 …
Loss of peroxisome redox balance occurs upon sustained peroxisome proliferation and has …

… Proteostasis is the dynamic regulation of a balanced, functional proteome, in order to … cells,
proteostasis is maintained by different quality control systems such as molecular chaperones, …

… Cellular stress caused by protein misfolding, aggregation and redox imbalance is typical
of neurodegenerative disorders such as Parkinson’s disease (PD) and Amyotrophic Lateral …

… (Prx-SO-OH), the protein forms higher molecular weight aggregates and switches its function
from an antioxidant to a molecular chaperone. In most cases, hyperoxidation from sulfenic …

… protein aggregates is the main characteristics of proteinopathies. Aging-induced interorganellar
redox imbalance, … However, ER-located proteins like the molecular chaperones BiP/…

… study ER redox homeostasis upon proteostasis imbalances and … redox imbalances are
communicated between tissues within … heat shock factor and molecular chaperones. Mol Biol Cell …

… recently studied the impact of SNO-PTMs on proteostasis in SH-SY5Y neuroblastoma cells
[50], … functions of molecular chaperone machineries. These molecules recognize and bind to …

… , cells express some classes of molecular chaperones that guide the nascent polypeptide …
molecular pathogenesis of neurodegeneration related to the disturbance of redox balance …

… In this article, we briefly overview the function of proteostasis mechanisms in cell aging with
an emphasis on molecular chaperones and their interrelationships with autophagy and UPS. …

… toxicity phenotypes associated with protein aggregation. Together, our data reveal that …
redox homeostasis may be central to proteostasis maintenance through autophagy regulation…