… Here I review recent evidence that cancer cells are prone to loss of proteostasis within the
ER, and hence may be susceptible to targeted interventions that either reduce homeostatic …

… Here, we review the differential scales of proteostasis regulation from the cellular to the …
performed by molecular chaperones is central to protein fate and cellular proteostasis. …

… unfolded protein response (UPR) and molecular chaperones … of death, beyond altering
the redox balance of the neuron, is … between the altered proteostasis network controlled by …

… and declining proteostasis control, are key contributors during … In the following sections, we
discuss how redox imbalance in … as a molecular chaperone interacting with α-syn; and (iv) the …

… Molecular processes involved in regulating the proteostasis … In case of protein
unfolding/misfolding molecular chaperones … in proteostasis control, including chaperones, redox …

… molecular chaperones, protein clearance pathways as well as stress-associated signaling
networks which work together to prevent protein … together form the proteostasis network which …

… to regulate protein synthesis; 2) molecular chaperones and co-chaperones responsible for
… proteins; 3) components of protein trafficking pathways to ensure protein proper location; 4) …

… at both basal conditions and under conditions of proteotoxic stress [15,16]. Key components
of the PN are the molecular chaperones … the cytosolic GSH redox balance in larvae muscles …

… protein aggregation and altered proteostasis are common features of sporadic and familial
ALS forms. The proteostasis … a collection of mechanisms related to protein synthesis, folding, …

… possible relationships between redox signalling and proteostasis. … , molecular chaperones
are also part of this cellular disaggregation machinery. There are many types of chaperones, …