… , as epidemiological studies found a high incidence of thromboembolic events similar to
that of chronic AF. … The molecular mechanisms governing the anticoagulant activity of …

… The molecular events that control the cellular and tissue expression of the TFPI isoforms are
… undergoes alternative splicing and acts as a molecular switch that blocks TFPIβ translation. …

… They have cast light on clinical events which had remained … in the large molecule of FVIII
could create a similar defect [17]. … /protein C ratio, a continuous prudent anticoagulation may be …

… an anticoagulant cofactor for both protein C and TFPI pathways. … the lipoproteins—the
molecular mechanisms involved in the … system is to regulate the alternative splicing event aiming …

… Protein C is a natural anticoagulant activated by thrombin in a reaction accelerated by the
cofactor thrombomodulin. The zymogen to protease conversion of protein C … similar molecular …

… have now been largely elucidated and the molecular events that lead to clot formation are
… protein C anticoagulant pathway. The protein C pathway is initiated when protein C bound …

… A defect in the protein C anticoagulant pathway is associated with a hypercoagulable state
that increases the clotting propensity of the blood, thereby resulting in pathological vascular …

… is one of the most important physiological anticoagulant … for protein and ions while TIP3P
model for all water molecules, … of VTE, including 5 with recurrent events, indicating a strong …

… to activated protein C (APC), an anticoagulant serine protease… might directly affect the protein
C pathway and, consequently… heme with either overlaying binding events, different binding …

… by heparin like molecules; – the protein C and S system, … in the genes of the anticoagulant
factors protein C, protein S and AT; … to procoagulant activity may be one of the early events in …