[HTML][HTML] Cellular and molecular mechanisms of anti-phospholipid syndrome

M Radic, D Pattanaik - Frontiers in immunology, 2018 - frontiersin.org
… anti-phospholipid syndrome (APS) is characterized by the production of antibodies that
bind the phospholipid-… Emerging concepts in the molecular pathogenesis of systemic lupus …

Pathogenesis and management of antiphospholipid syndrome

DRJ Arachchillage, M Laffan - British journal of haematology, 2017 - Wiley Online Library
… review is to examine the evolving understanding of APS pathogenesis and how this and
other therapeutic options will change the way we manage this potentially devastating disorder. …

Insights into the diagnosis and pathogenesis of the antiphospholipid syndrome

MHA Noureldine, W Nour-Eldine… - Seminars in Arthritis and …, 2019 - Elsevier
… Anticardiolipin or Hughes syndrome, is a systemic autoimmune disorder characterized …
antiphospholipid antibodies (aPL). The contribution of the extra-criteria aPL to the pathogenesis

The antiphospholipid syndrome: from pathophysiology to treatment

S Negrini, F Pappalardo, G Murdaca, F Indiveri… - Clinical and …, 2017 - Springer
… Moreover, aPL interacting with endothelial cells may induce the expression of adhesion
molecules such as intercellular cell adhesion molecule-1, vascular cell adhesion molecule-1, E-…

The pathophysiology of the antiphospholipid syndrome: a perspective from the blood coagulation system

R Arreola-Diaz, A Majluf-Cruz… - Clinical and Applied …, 2022 - journals.sagepub.com
antiphospholipid syndrome (… antiphospholipid antibodies such as lupus anticoagulant,
anti-β-2-glycoprotein 1, and/or anticardiolipin antibodies. In the obstetrical APS, antiphospholipid

[HTML][HTML] Advances in the pathophysiology of thrombosis in antiphospholipid syndrome: molecular mechanisms and signaling through lipid rafts

A Capozzi, V Manganelli, G Riitano, D Caissutti… - Journal of Clinical …, 2023 - mdpi.com
… of antiphospholipid syndrome (APS) are related to the activity of circulating antiphospholipid
… In this review, we describe the pathogenic mechanisms of APS through the key role of lipid …

[HTML][HTML] Oxidative Stress in the Pathogenesis of Antiphospholipid Syndrome: Implications for the Atherothrombotic Process

C Nocella, S Bartimoccia, V Cammisotto, A D'Amico… - Antioxidants, 2021 - mdpi.com
Atherothrombosis is a frequent complication of the clinical history of patients with antiphospholipid
syndrome (APS). Both atherothrombosis and APS are characterized by increased …

[HTML][HTML] Mechanisms of immunothrombosis and vasculopathy in antiphospholipid syndrome

JS Knight, Y Kanthi - Seminars in immunopathology, 2022 - Springer
… also key drivers of APS pathophysiology. Thrombotic events in … This review will highlight
known pathogenic factors in APS … a barrier that selectively permits molecular and cellular transit …

Oxidative stress in the pathogenesis of atherothrombosis associated with anti-phospholipid syndrome and systemic lupus erythematosus: new therapeutic approaches

C Lopez-Pedrera, N Barbarroja… - …, 2016 - academic.oup.com
… the reduction of antioxidant molecules. This imbalance causes … -inflammatory and procoagulant
molecules, the formation of … stress in the pathogenesis of atherothrombosis associated …

[HTML][HTML] Antiphospholipid syndrome in pregnancy: new and old pathogenetic mechanisms

S D'Ippolito, G Barbaro, C Paciullo, C Tersigni… - … journal of molecular …, 2023 - mdpi.com
syndrome. The aim of this review is to investigate the state-of-the-art antiphospholipid syndrome
pathogenesis … examining all of the known pathogenetic mechanisms contributing to the …