… amyloid fibrils exhibit polymorphism at the molecular level, ie, a … of different types of secondary
structure elements, such as α-… that these differences in the structures of full-length (1–140) …

… of the molecular level details that define the structural diversity … (A) Simplified depiction of
the three regions of α-synuclein that … state due to its lack of secondary structure. As a result, it …

… We further analyzed the secondary structure of α-synuclein monomers and dimers. The …
The stability of polymorphic α-synuclein dimers derived from experimentally determined fibrils by …

… Our study has shown that at the molecular level so far there … experiment that proposed the
secondary structure (ie, β-… We further investigated the structural stability of the full-length AS(1–…

… According to the three regions (NTD, NAC, and CTD) and the secondary structure properties
… reveal the mechanism and specific structural details from the molecular level of α-syn dimer …

Numerous Alpha-synuclein amyloid structures available in PDB enable their comparative
analysis. They are all characterized by a flat structure of each individual chain with an …

… polymorphic structures of in vitro generated amyloid fibrils of α-Syn (denoted polymorphs 2a
and 2b). Our structures … fibril structure, and contribute to our understanding of amyloid fibril …

… that probes at the molecular level the specific interactions … Based on these four AS fibrils, we
constructed four full-length AS … of the secondary structure of the protein (DSSP) method. The …

… and temporal evolution of polymorphism. We follow morphological … full length fibrils are
suggested to have a different structure … in wt αSyn in terms of secondary structure, we performed …

… The secondary structure of A53T recorded in this study was similar to that determined by …
replica exchange molecular dynamics (REMD) simulations on the full-length monomeric WT …