… using Cox proportional hazards regression models. Patients were censored at … monitoring
plan approach is being implemented in some centers using the genetic profile and monitoring …

… , because the early institution of appropriate therapy can prevent multiorgan damage and
death. This review focuses on atypical HUS, a subtype of HUS, caused by a dysregulated …

… However, considering the risk of relapse(s), close monitoring … interviewers explained the
IPH model after which participants … trained in aHUS disease characteristics and the IPH model. …

… Herein, we will focus on one of these conditions, atypical hemolytic uremic syndrome (aHUS…
, now commonly called Shiga toxin-associated hemolytic uremic syndrome (STEC-HUS), …

Atypical hemolytic uremic syndrome (aHUS) is an ultrarare disease caused, in most cases,
by dysregulation of the alternative complement (C′) pathway at the surface of the vascular …

… such a model and explored alternative dosing regimens to improve early treatment response
… observational study to monitor the new guideline concerning the treatment of patients with …

… 1 dose of eculizumab for treating aHUS. A linear mixed effects model was used with random
… can be safely monitored off eculizumab and prompt reinitiation of treatment on recurrence …

… A transgenic murine model of aHUS arising from a loss-of-function mutant CFH protein that
… monitor patients over the long term and assess if discontinuation of long-term therapy is …

… model, we could not compare high- versus moderate- versus low-risk groups because this
model … The renal status of each patient was monitored over time (Figure 6B). New adult-onset …

… This study will include all aHUS patients and will monitor and evaluate the restrictive
treatment regimen according to the new Dutch guideline. With the CUREiHUS study we hope to …