… mouse models for the study and elucidation of the pathophysiological mechanisms underlying
atherosclerosis… can result in vascular inflammation and atherosclerosis. Finally, novel …

… the choice of an atherosclerotic mouse model. This scheme should help current and future
researchers to choose the most appropriate atherosclerotic mouse model based on their …

… atherosclerosis-related phenotypes in mice and humans. We briefly discuss the development
of mouse models … and genetic studies of atherosclerosis using mouse models. Altogether, …

… are the two most frequently used mouse models for atherosclerosis, also ApoE3-Leiden
mice are utilized in many studies. Apolipoprotein (Apo)E3-Leiden is associated with a genetic …

… In this review, we examine the main mouse models of atherosclerosis currently available,
their method … The aim is to identify which, if any, mouse model of atherosclerosis is suitable for …

… and inflammation, and a consideration of suitable animal models, both mouse and non-mouse
models, as addressed in this review, which add to the value of atherosclerosis research. …

… PCSK9-AAV mice were a new line of mouse models for atherosclerosis research created
by two groups (57,58). One of the best advantages of these mice is that atherosclerotic lesions …

… atherosclerotic plaques in the 1980s. The new immunologic tools together with genetically …
mouse models laid the foundation for deciphering the inflammatory etiology of atherosclerosis …

… relationship and relevant atherosclerotic pathology observed in porcine systems (71,72),
drug testing is predictive for efficacy of drugs in humans compared to the mouse model. It can …

… atherosclerosis development, the study design was planned in such a way that, initially,
mouse model of atherosclerosis (… Twenty male C57BL/6 mouse model of atherosclerosis were …