Crystallographic studies on protein misfolding: Domain swapping and amyloid formation in the SH3 domain

A Cámara-Artigas - Archives of Biochemistry and Biophysics, 2016 - Elsevier
… The β-sheet structure is the principal molecular structure of … where the amyloid has been
obtained in vitro from peptides or … predicted its formation by molecular dynamics calculations […

Mechanistic insights into proteins association through molecular dynamics

KP Chua - 2017 - dr.ntu.edu.sg
… out of 13 binding partners of Abl SH3 domain directly from the human genome… two peptides
were identified in Section 3.3.2. As such, we hypothesize the formation of inter-chain β-sheet

Hydrogen-deuterium exchange mass spectrometry reveals folding and allostery in protein-protein interactions

CA Ramirez-Sarmiento, EA Komives - Methods, 2018 - Elsevier
… FRET, and molecular dynamics simulations with HDXMS. In this … the data from eight peptides
distributed across the whole … ), which form a β-sheet within the same polypeptide chain only …

[PDF][PDF] The small β-barrel domain: a survey-based structural analysis

P Youkharibache, S Veretnik, Q Li, KA Stanek, C Mura… - Structure, 2019 - cell.com
domain, we explore the anatomy of the SBB and its representative structural variants. Many
… ), the intact SBB forms only by binding of the cognate peptide ligand (Figure 5B). HP1 exists …

[HTML][HTML] Cardiovascular functions of ena/VASP proteins: past, present and beyond

PM Benz, T Frömel, H Laban, J Zink, L Ulrich… - Cells, 2023 - mdpi.com
… ActA peptide DFPPPPTDEEL to the Mena EVH1 domain can … intramolecular binding of the
Abl SH3 domain is important to … end of the second β-sheet of the EVH1 domain, opposite of its …

Computational Analysis of Thermodynamic Factors for Intrinsically Disordered Ligand Recognition

J Shi - 2021 - oaktrust.library.tamu.edu
… For that reason, molecular dynamics (MD) simulation is used to … an SH3 domain from the Abl
kinase complexed with several … Since the unbound peptides undergo drastic conformational …

Peptide Based Biosensors And Mass Spectrometric Methods To Measure The Activation Of Tyrosine Kinases

RJ Schuster - 2016 - search.proquest.com
… is maintained through multiple intramolecular interactions. The … The ABL SH3 domain ligand
binds to the ABL SH3 domain, … 167 The GB1 protein contains α-helix, β-sheet, loop and turn …

Cloning and characterisation of alternansucrase from Leuconostoc citreum ABK-1 and role of surface aromatic acids on product size

K Wangpaiboon - 2017 - digital.car.chula.ac.th
… The two versions of truncated SH3-like domains,∆ 3SHALT and∆ 7SHALT, were successfully
constructed. The WTALT,∆ 3SHALT and∆ 7SHALT possessed optimum temperature of 40 C…

[HTML][HTML] PQBP1: The key to intellectual disability, neurodegenerative diseases, and innate immunity

H Tanaka, H Okazawa - International Journal of Molecular Sciences, 2022 - mdpi.com
Many studies have supported this hypothesis by … polyQ sequence, which adopts a β-sheet
structure, functions as a … an elongated CAG repeat peptide flanked with short sequences …

Simple fluorogenic cellular assay for histone deacetylase inhibitors based on split-yellow fluorescent protein and intrabodies

Y Ohmuro-Matsuyama, T Kitaguchi, H Kimura… - ACS …, 2021 - ACS Publications
two fragments, FP1-10 (the region from the N-terminus to the 10th) and FP11 (the 11th β-sheet
In addition, 2 days after the transfection, several cells expressing FP11-scFv-APP showed …