The role of polyamine metabolism in cellular function and physiology

RS Schibalski, AS Shulha, B Tsao… - … of Physiology-Cell …, 2024 - journals.physiology.org
Polyamines are molecules with multiple amino groups that … be a compensatory mechanism
to maintain 250 polyamine levels … During cardiac hypertrophy, TRPV1 is elevated and 459 …

Correlation between endogenous polyamines in human cardiac tissues and clinical parameters in patients with heart failure

C Meana, JM Rubin, C Bordallo… - Journal of cellular …, 2016 - Wiley Online Library
… , polyamines have also been related to several cardiac pathological conditions and diseases,
such as hypertrophy … might be a compensatory mechanism to preserve cardiac contractility. …

[HTML][HTML] Polyamine homeostasis in development and disease

S Nakanishi, JL Cleveland - Medical Sciences, 2021 - mdpi.com
… SPD delays cardiac aging by reducing hypertrophy and improving … Interestingly, ASS1 loss
is associated with compensatory … We acknowledge the many outstanding scientists that have …

[HTML][HTML] Dynamic mitochondrial proteome under polyamines treatment in cardiac aging

H Zhang, M Yan, T Liu, P Wei, N Chai, L Li… - Frontiers in Cell and …, 2022 - frontiersin.org
Polyamines play multiple roles in the cellular process, such as stabilizing and remodeling
chromosomes, stimulating cell proliferation, and protecting cells under different types of stress (…

[HTML][HTML] Right ventricle remodeling metabolic signature in experimental pulmonary hypertension models of chronic hypoxia and monocrotaline exposure

T Hautbergue, F Antigny, A Boët, F Haddad, B Masson… - Cells, 2021 - mdpi.com
… Some compensatory reactions are probably promoted to slow down … polyamines are involved
in the development of cardiac hypertrophy and that cardiac injury is partly offset by several

[图书][B] Understanding the evidence-based Role played by Polyamines in Vascular Pathophysiology in animal models of (re) stenosis at molecular level.

H Saboowala - 2020 - books.google.com
… are produced by an intracellular highly regulated pathway or … 1 below) through the addition
of one and two aminopropyl … to compensatory mechanisms leading to homeostasis of cellular …

ATP13A3 variants promote pulmonary arterial hypertension by disrupting polyamine transport

B Liu, M Azfar, E Legchenko, JA West… - Cardiovascular …, 2024 - academic.oup.com
… by ATP13A3 deficiency, suggesting a lack of compensation by these related proteins. We
found … This probably explains why multiple endogenous polyamine species are simultaneously …

Angiocrine polyamine production regulates adiposity

E Monelli, P Villacampa, A Zabala-Letona… - Nature …, 2022 - nature.com
… However, we observed vascular hyperplasia in the Pten iΔEC WAT, … may be important in
many other biological contexts. … Participants of the study did not receive any compensation. …

Polyamine Biosynthetic Metabolic Dysregulation: Targeting and the Adaptive Response

S Rosario - 2020 - search.proquest.com
… who will be poised to benefit most from polyamine-targeted therapies……………………………
two have truly helped to guide me in every aspect of my life and I am looking forward to many

[HTML][HTML] Mechanism of histone deacetylases in cardiac hypertrophy and its therapeutic inhibitors

Y Han, J Nie, DW Wang, L Ni - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
… to multiple cardiac diseases, especially in cardiac hypertrophy. … is generally considered to
be a compensatory effect that … HDAC10 has been identified as a polyamine deacetylase, with …