[HTML][HTML] Anti-neurodegenerative benefits of acetylcholinesterase inhibitors in Alzheimer's disease: Nexus of cholinergic and nerve growth factor dysfunction

DE Moss, RG Perez - Current Alzheimer research, 2021 - ncbi.nlm.nih.gov
… in the myelination of neurons [80]. AChE and BChE also impact muscarinic and nicotinic …
of nicotinic cholinoceptive neurons, as well as improved CNS cholinergic signaling [87]. …

Cholinergic Imaging and Dementia

N Okkels, J Horsager, N Pavese, DJ Brooks… - … Disorders, 2023 - Springer
… by cholinergic as well as cholinoceptive non-cholinergic neurons. Upon release from the
cholinergic neuron, acetylcholine can bind to metabotropic muscarinic receptors or ionotropic …

[HTML][HTML] Cellular, synaptic and network effects of acetylcholine in the neocortex

C Colangelo, P Shichkova, D Keller… - Frontiers in neural …, 2019 - frontiersin.org
… the frontal cortex, parietal cortex, temporal cortex, entorhinal … Muscarinic cholinergic
activity influences sensory processing … The detection of cholinoceptive structures such as the …

Cholinergic changes in Lewy body disease: implications for presentation, progression and subtypes

N Okkels, MJ Grothe, JP Taylor, SG Hasselbalch… - Brain, 2024 - academic.oup.com
… parietal, 19 occipital, and frontal lobes.Given the absence of … 17 increased availability of
muscarinic receptors, which may … 8 Lewy body disease can impact cholinergic neurons in both …

[HTML][HTML] Central Nicotinic and Muscarinic Receptors in Health and Disease

Y Tizabi, B Getachew, V Tsytsarev… - … Recent Advances and …, 2023 - intechopen.com
prefrontal cortex excitatory networks that underlie working memory function [28, 29]. Moreover,
… Visualization of cholinoceptive neurons in the rat neocortex: Colocalization of muscarinic

Enhanced prefrontal nicotinic signaling as evidence of active compensation in Alzheimer's disease models

SK Power, S Venkatesan, S Qu, JA McLaurin… - bioRxiv, 2023 - biorxiv.org
… We next evaluate whether muscarinic components of the cholinergic synapse are also …
Nicotinic cholinoceptive neurons of the frontal cortex are reduced in Alzheimer’s disease. …

Outcome-locked cholinergic signaling suppresses prefrontal encoding of stimulus associations

G Tu, A Halawa, X Yu, S Gillman… - Journal of …, 2022 - Soc Neuroscience
… affected in Alzheimer's disease, our … of cortical ACh originates from the cholinergic neurons
in the basal forebrain (BF), which consists of several subregions projecting to specific cortical

[HTML][HTML] Cholinergic stress signals accompany MicroRNA-associated stereotypic behavior and Glutamatergic Neuromodulation in the Prefrontal Cortex

G Moshitzky, S Shoham, N Madrer, AM Husain… - Biomolecules, 2020 - mdpi.com
… SB and reaction to the muscarinic stimulator pilocarpine. At the … the protein level, cholinergic
neurons in TgR mice appeared … TgR hippocampus reflect its cholinoceptive features; to test …

Layer specific distribution of muscarinic receptor M2 in the the sensorimotor areas of rat brain

S Yusufoğlulları - 2018 - 193.140.201.98
… Thus, remote control of the cortex can be conducted by prefrontal cortex [4, 22–29]. …
cholinoceptive neurons which have both nicotinic and muscarinic ACh receptors. Hence, the memory …

[PDF][PDF] Contribution of Cholinergic Innervation to Adult Hippocampal Neurogenesis in Dementia

C Jantrachotechatchawan - 2019 - kclpure.kcl.ac.uk
… Aberrations in the adult hippocampal neurogenesis in AD patients include dysfunctional
maturation indicated by accumulated number of immature neurons. The hippocampus receives …