… muscular dystrophy (DMD) is caused by loss-of-function mutations in the dystrophin gene
on chromosome … degradation of the destabilized dystrophin-associated protein complex [154]. …

… skeletal muscle disorder, Duchenne muscular dystrophy (DMD) … component of the
dystrophin-associated protein complex, … In-frame mutations leading to truncation of the protein …

… muscular dystrophy with a proximal weakness in the limb-girdle … dystrophin- associated
SGC complex that fails to localize at the … for α- and γ-sarcoglycan showed an absent reaction. …

… mutations in the SGCG gene, which encodes the dystrophin-associated protein γ-sarcoglycan…
the treatment of Duchenne muscular dystrophy (DMD), which is caused by mutations in the …

… dystrophin-associated glycoprotein complex, and its expression is respectively deficient in
limb girdle muscular dystrophy … deficiency of membrane protein γ-sarcoglycan, but no ectopic …

… gene in chromosome 13 results in a stop codon and premature truncation of the protein at
codon 24… The SCGC mutation results in abnormal γ-sarcoglycan protein,5 which functions as a …

… mutation of the γ-sarcoglycan gene and no γ-sarcoglycan … proteins was observed in the
high-dose cohort, indicating that SRP-9003 may also restore the dystrophin-associated protein …

… a 427-kDa cytoplasmic protein predominantly expressed in striated muscle (1). Mutations in
… lead to Duchenne muscular dystrophy (DMD) or Becker muscular dystrophy, a milder form of …

… skeletal muscular dystrophies in … mutants showed impaired E3 ubiquitin ligase activity
toward dysbindin in COS-7 cells [58]. Dysbindin is a member of the dystrophin-associated protein …

… from mutations that disrupt the γ-sarcoglycan (SGCG) gene. SGCG is a dystrophin associated
protein and its null mutations … gamma-sarcoglycan in chromosome 13 muscular dystrophy …