… Duchenne muscular dystrophy (DMD) is a lethal muscle-wasting disease currently
without cure. We investigated the use of the PiggyBac transposon for full-length dystrophin …

… type of muscular dystrophy, Duchenne muscular dystrophy (DMD), is caused by mutations in
the X-linked dystrophin gene… Clinical data demonstrated that muscles treated with myoblast …

… Over the past decade different stem cell (SC) based approaches were tested to treat Duchenne
Muscular Dystrophy (DMD), a lethal X-linked disorder caused by mutations in dystrophin …

… dystrophin expression correlating with improved function after transplantation of dystrophin
expressing chimeric (DEC) cells of myoblast … cell line of myoblasts and mesenchymal stem …

… effects on muscle health and is an underlying cause of muscle … cell dysfunction in Duchenne
muscular dystrophy (DMD), to … are transferred to DMD muscle tissue during myoblast fusion, …

… cell transplantation and numerous efforts to optimize cell culture conditions in a lab setting,
the use of myoblasts or satellite cells to treat DMD in the clinic has not been realized yet. …

… fully applied to the hiPSCs of muscular dystrophy, mainly due to the absence of a successful
strategy for isolating expandable functional myoblasts. Previous efforts to derive myogenic …

… Genome editing of the dystrophin gene has been successful in cultured myoblasts, induced
pluripotent stem cells, and fibroblasts with zinc finger nucleases, TALENs, meganucleases, …

… Duchenne muscular dystrophy (DMD) is a muscular disorder … reduction of the muscle
cytoskeletal protein dystrophin. The … into myoblasts upon injury to generate new muscle fibers [69]…

… human myoblasts from healthy controls, Duchenne patients and mdx mice. Treatment of
myoblasts … To demonstrate that the transferred miR-29c played a role in the increased myoblast …