… inhibits sodium potassium adenosine triphosphatase (Na + /K + -ATPase) and in the
myocardium it increases the intracellular level of sodium and calcium ions in the myocytes thus …

… Renal function is an important index for digoxin dose … Typical values for clearance and volume
of distribution were 2.67 … Digoxin enhanced myocardial contractility and improved ejection …

… study suggests digoxin may adversely affect renal function in … is warranted to elucidate
digoxin's renal effects in CHF patients. … levels in neonates treated with digoxin after delivery [9]. …

… digoxin in this study was the large availability of clinical data to support the estimation and
verification of mechanistic kidney … conflicting reports that digoxin volume of distribution may be …

… As the volume of distribution is smaller in patients with severe renal failure that normal subjects…
intracellular calcium in myocardial cells, patients with renal dysfunction are more prone to …

… Multivariable Cox proportional hazards and sub-distribution … events or renal function decline
in advanced CKD patients. … heart rate and increases myocardial contractility by inhibiting …

… on the myocardial cells and on the cardiac conduction system 2 . … renal function but it may
be doubled in renal impairment or … CHF, which decreased the volume of distribution of digoxin. …

… and myocardial contractility and modulates neurohormonal abnormalities in patients with
heart … Digoxin has a large volume distribution (4–8 L/kg) and is distributed mainly in skeletal …

… inhibits sodium potassium adenosine triphosphatase (Na+/K+-ATPase) and in the
myocardium it increases the intracellular level of sodium and calcium ions in the myocytes thus …

… digoxin-treated AF patients (age, 68±11 years; male, 40.3%) was 12.1%. These fatalities
resulted from heart failure (46.1%), fatal stroke (26.9%), fatal myocardial … heart disease (IHD), …