[HTML][HTML] Three-dimensional (3D) hydrogel serves as a platform to identify potential markers of chondrocyte dedifferentiation by combining RNA sequencing

Y Ling, W Zhang, P Wang, W Xie, W Yang, DA Wang… - Bioactive materials, 2021 - Elsevier
… We hypothesized that chondrocyte's mRNA expression must be changed along with their …
crosstalk between chondrocytes and ECM, but also in regulating linkages between collagens …

Inhibitory Effect of a Tankyrase Inhibitor on Mechanical Stress-Induced Protease Expression in Human Articular Chondrocytes

Y Hotta, K Nishida, A Yoshida, Y Nasu… - International Journal of …, 2024 - mdpi.com
… -induced gene expression in human chondrocytes and examined TNKS-1/2 expression in
… Our data also suggested that mechanical stimulation up-regulated the expression of TNKS-1…

[PDF][PDF] RETRACTED ARTICLE: TMF inhibits miR-29a/Wnt/β-catenin signaling through upregulating Foxo3a activity in osteoarthritis chondrocytes

X Huang, Z Chen, W Shi, R Zhang, L Li… - Drug design …, 2019 - Taylor & Francis
… of chondrocytes apoptosis, gene expression, and protein … down regulated the
expression of Foxo3a and up regulated the … the expression of miR-29a by binding of β-catenin/TCF4/LEF1

Epigenetic therapies for osteoarthritis

FC Grandi, N Bhutani - Trends in pharmacological sciences, 2020 - cell.com
expression protected mice from surgically induced OA. Mechanistically, this was in part
due to increased mitochondrial metabolism in chondrocytes upon genetic loss of Dnmt3b [ …

Regulation of osteoarthritis hypoxia-inducible factor-2 alpha regulatory mechanism and application prospect

C Yang, L Zhang, L Zhou, J Zhao - Chinese Journal of Tissue Engineering …, 2016 - cjter.com
… directly regulating the expressions of various catabolic genes … on the chondrocytes by
regulating the expressions of Wnt/β-… HIF-2 alpha mRNA expression in osteoarthritic chondrocytes. …

The expression of SIRT1 in articular cartilage of patients with knee osteoarthritis and its correlation with disease severity

Y Li, W Xiao, P Wu, Z Deng, C Zeng, H Li… - Journal of orthopaedic …, 2016 - Springer
… -specific gene expression in chondrocytes derived from … in chondrocytes and its deficiency
may lead to chondrocyte … that SIRT1 could regulate apoptosis in chondrocytes through …

[HTML][HTML] Role and mechanisms of the NF-ĸB signaling pathway in various developmental processes

P Liu, Y Li, W Wang, Y Bai, H Jia, Z Yuan… - Biomedicine & …, 2022 - Elsevier
… /p50) regulated the expression of protein tyrosine phosphatase … Gene Expression Omnibus
database comparing human amniocytes from patients with spina bifida and healthy controls

Stromal-Cell-Derived Factor-1 (SDF-1) Down-Regulates ANKH via NF-kB Promote Formation of Chondrocyte Mineralization.

Y Zhu, T Liu, Y Tong, M Gu, J Li, R Hao, C Wang, L Guo - 2021 - researchsquare.com
… , et al: LEF1-mediated MMP13 gene expression is repressed by SIRT1 in human chondrocytes.
… V and Karin M: IKKalpha limits macrophage NF-kappaB activation and contributes to the …

Paeonol inhibits inflammatory response and protects chondrocytes by upregulating sirtuin 1

P Shang, Y Liu, J Jia - Canadian Journal of Physiology and …, 2022 - cdnsciencepub.com
… , the activation of which may be suppressed by paeonol through regulating SIRT1. … suppressing
phosphorylation and acetylation of p65 NF-kappaB and STAT3. Redox Biol. 38: 101813. …

Oroxylin A attenuates osteoarthritis progression by dual inhibition of cell inflammation and hypertrophy

DH Chen, G Zheng, XY Zhong, ZH Lin, SW Yang… - Food & function, 2021 - pubs.rsc.org
… , where it regulates the transcription of Wnt target genes with the … IL-1β induced primary
human chondrocytes and surgically … studied inhibitory targets which are Dvl2, LEF-1, and TCF-4. …