Nanoparticles exhibiting virus-mimic surface topology for enhanced oral delivery
Z Sang, L Xu, R Ding, M Wang, X Yang, X Li… - Nature …, 2023 - nature.com
… of viruses to tissues and cells, we construct an efficient oral Nano-DDS … mimicking both the
structure and function of viruses. We first prepare mesoporous silica NPs with nanoscale virus-…
structure and function of viruses. We first prepare mesoporous silica NPs with nanoscale virus-…
Bio-inspired engineering of cell-and virus-like nanoparticles for drug delivery
… here an overview of virus- and cell-derived biomimetic delivery systems that combine the …
This mimicking of the surface topology of viruses bestowed nanoparticles with increased …
This mimicking of the surface topology of viruses bestowed nanoparticles with increased …
Why synthetic virus-like nanoparticles can achieve higher cellular uptake efficiency?
… by mimicking the spiky surfaces of viruses; however, little is … as oral delivery vectors
with enhanced delivery efficiency. The … on how the virus-like surface topology affects NP–bilayer …
with enhanced delivery efficiency. The … on how the virus-like surface topology affects NP–bilayer …
Advances in nanoparticle development for improved therapeutics delivery: nanoscale topographical aspect
… nm) Virus-mimicking rough surface To enhance both absorptions of biomolecules and cellular
uptake Influence of nanoscale surface … The virus mimicking surface topography was also …
uptake Influence of nanoscale surface … The virus mimicking surface topography was also …
Carrier-free nanodrug-based virus-surface-mimicking nanosystems for efficient drug/gene co-delivery
… surface of virus, which has been identified to favor cellular … -viral nanoparticle mimicking
virus surface topography. It was demonstrated that the nanoscale surface roughness enhanced …
virus surface topography. It was demonstrated that the nanoscale surface roughness enhanced …
Spiky nanostructures with geometry-matching topography for virus inhibition
C Nie, M Stadtmüller, H Yang, Y Xia, T Wolff… - Nano …, 2020 - ACS Publications
… better to virions than smooth nanoparticles, due to the … virus replication at the cellular nontoxic
dosage. We predict that such a combination of geometry-matching topography and cellular …
dosage. We predict that such a combination of geometry-matching topography and cellular …
Facile synthesis of uniform virus-like mesoporous silica nanoparticles for enhanced cellular internalization
W Wang, P Wang, X Tang, AA Elzatahry… - ACS central …, 2017 - ACS Publications
… a rough structure mimicking the spike proteins of a virus. The … virus-like rough surface, the
mesoporous silica nanoparticles … nanoparticles (28%), suggesting excellent drug delivery …
mesoporous silica nanoparticles … nanoparticles (28%), suggesting excellent drug delivery …
Bioinspired nanotopographical design of drug delivery systems
JA Finbloom, C Huynh, X Huang… - Nature Reviews …, 2023 - nature.com
… Virus-inspired topographical nanoneedles can improve … may better mimic the nanoneedle
injectors of natural viruses, … For example, virus-inspired mesoporous silica nanoparticles …
injectors of natural viruses, … For example, virus-inspired mesoporous silica nanoparticles …
Virus spike and membrane-lytic mimicking nanoparticles for high cell binding and superior endosomal escape
… for gene therapy have attracted increasing attention because viral … , such as capsid, surface
topography, and nucleic acid … -disruptive virus mimic for gene delivery. Bioreducible cross-…
topography, and nucleic acid … -disruptive virus mimic for gene delivery. Bioreducible cross-…
Biomimetic nanomaterial strategies for virus targeting: Antiviral therapies and vaccines
JA Jackman, BK Yoon, L Ouyang… - Advanced Functional …, 2021 - Wiley Online Library
… vi) Biomimetic nanoparticle vaccines that mimic the … , targeted delivery, and/or improved
safety of viral replication inhibitors… A virus (IAV) particle based on geometry-matching topology. f) …
safety of viral replication inhibitors… A virus (IAV) particle based on geometry-matching topology. f) …