Gram-scale synthesis of highly biocompatible and intravenous injectable hafnium oxide nanocrystal with enhanced radiotherapy efficacy for cancer theranostic
Y Li, Y Qi, H Zhang, Z Xia, T Xie, W Li, D Zhong, H Zhu… - Biomaterials, 2020 - Elsevier
… nanoparticles with the composition of hafnium oxide (HfO 2 is an oxides compound made of
hafnium (… Phase II/III clinical trial for radiotherapy. Once the HfO 2 NPs accumulates in tumor …
hafnium (… Phase II/III clinical trial for radiotherapy. Once the HfO 2 NPs accumulates in tumor …
Hafnium oxide nanoparticle activated by radiation therapy generates an anti-tumor immune response
J Galon, M Laé, JO Thariat, S Carrere… - International Journal of …, 2018 - redjournal.org
… density material, hafnium oxide, was designed at the nanoscale to efficiently absorb …
nanoparticles (HfO2-NP), delivered into the tumor by a single injection and activated by radiotherapy…
nanoparticles (HfO2-NP), delivered into the tumor by a single injection and activated by radiotherapy…
NBTXR3 radiotherapy-activated functionalized hafnium oxide nanoparticles show efficient antitumor effects across a large panel of human cancer models
P Zhang, J Marill, A Darmon… - International Journal …, 2021 - Taylor & Francis
… potential of radiotherapy to treat cancers, the first-in-class radioenhancer NBTXR3 (functionalized
hafnium oxide nanoparticles) has been designed to amplify the effects of radiotherapy. …
hafnium oxide nanoparticles) has been designed to amplify the effects of radiotherapy. …
Synthesis and bioapplication of emerging nanomaterials of Hafnium
… has been commonly used for obtaining nanoscale hafnium oxide NPs. The initial step is …
In a similar approach to radiotherapy applications, nanoscale hafnium materials may be …
In a similar approach to radiotherapy applications, nanoscale hafnium materials may be …
NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma …
S Bonvalot, PL Rutkowski, J Thariat, S Carrère… - The Lancet …, 2019 - thelancet.com
… patients with soft-tissue sarcoma when radiotherapy is applied preoperatively. In our phase
… 50 nm crystalline hafnium oxide (HfO 2 ) nanoparticles (NBTXR3) plus radiotherapy in soft-…
… 50 nm crystalline hafnium oxide (HfO 2 ) nanoparticles (NBTXR3) plus radiotherapy in soft-…
Hafnium oxide-based nanoplatform for combined chemoradiotherapy
AA Sherstiuk, SA Tsymbal, AF Fakhardo… - ACS Biomaterials …, 2021 - ACS Publications
… compounds, imaging, and an enhanced radiotherapy outcome. HfO 2 … without nanoparticles.
These results provide an important foundation for the development of complex nanoscale …
These results provide an important foundation for the development of complex nanoscale …
Selective Organ‐Targeting Hafnium Oxide Nanoparticles with Multienzyme‐Mimetic Activities Attenuate Radiation‐Induced Tissue Damage
D Liu, F Cao, Z Xu, C Zhao, Z Liu, J Pang… - Advanced …, 2024 - Wiley Online Library
… To selectively protect these sensitive organs during radiotherapy, we rationally designed
and synthesized a panel of LiT, LuT, and KiT HfO2 NPs with ROS scavenging capacities that …
and synthesized a panel of LiT, LuT, and KiT HfO2 NPs with ROS scavenging capacities that …
Radiotherapy-activated hafnium oxide nanoparticles produce abscopal effect in a mouse colorectal cancer model
P Zhang, A Darmon, J Marill… - International Journal …, 2020 - Taylor & Francis
… Hafnium oxide nanoparticles (NBTXR3) have been designed to increase energy dose
deposit within cancer cells. We examined the effect of radiotherapy-activated NBTXR3 on anti-…
deposit within cancer cells. We examined the effect of radiotherapy-activated NBTXR3 on anti-…
Advances of hafnium based nanomaterials for cancer theranostics
J Wang, J Pan, Y Tang, J Chen, X Fei, W Xue… - Frontiers in …, 2023 - frontiersin.org
… of Hafnium-based nanomaterials including Hafnium oxide … Hf oxide NMs, Hafnium
Metal-Organic Frameworks/nanoscale … reported hafnium-based material enhanced radiotherapy. …
Metal-Organic Frameworks/nanoscale … reported hafnium-based material enhanced radiotherapy. …
Hafnium-doped hydroxyapatite nanoparticles with ionizing radiation for lung cancer treatment
… metallic nanoparticles with composition of hafnium oxide (HfO 2 ) [12]. HfO 2 nanoparticle …
been shown that HfO 2 nanoparticles could enhance the effect of radiation therapy to kill the …
been shown that HfO 2 nanoparticles could enhance the effect of radiation therapy to kill the …
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