… The subsequent maturation of these nascent adhesions into FAs was blocked by knockdown
… more important than its tension-generating function for maturation of nascent adhesions [8]. …

… The C-terminus of paxillin contains four LIM domains, which are responsible for its FA targeting,
… , FA maturation and the formation of strong traction forces at FAs, although their random …

… Cells perform these functions and are so regulated via the formation of focal adhesions (…
nascent adhesion clusters as sketched in Figure 1a, that we analyze herein. The cell’s adhesion …

… disassembly due to myosin-II mediated traction force generation. … disassembly remain to
be elucidated, our study provided strong evidence in favor of a new model of this process. We …

… Reminiscent of two previous studies, the assembly of nascent adhesions at the leading …
[44]; and nascent adhesions are responsible for the generation of propulsive forces in migrating …

… Nascent focal adhesion (FA) sites start to emerge under the … between adhesion and
intracellular force generation and … a large part of the response may not contribute to propulsion. …

… Nascent focal adhesions are responsible for the generation of strong propulsive forces in
migrating fibroblasts. J Cell Biol 2001; 153:881-7; PMID:11352946; https://doi.org/10.1083/jcb.…

… We find that talin in focal adhesions is under tension, which is higher in peripheral than
central adhesions. Tension on talin is increased by vinculin and depends mainly on actin-binding …

… feedback loop, whereby adhesion-based signaling promotes generation of barbed ends at,
… stationary nascent adhesions either disassemble or grow to form larger focal adhesions ( …

… of actin filaments responsible for generating forces to propel the … directed cell migration begin
as nascent adhesions. These … high forces, the bond between these molecules is not strong …