[HTML][HTML] Activation strategies for invariant natural killer T cells

AC Kohlgruber, CA Donado, NM LaMarche… - Immunogenetics, 2016 - Springer
… also constitutively express receptors for inflammatory cytokines typically secreted by
antigen-presenting cells (APCs) after recognition of pathogen-associated molecular patterns (…

[HTML][HTML] α-Glucuronosyl and α-glucosyl diacylglycerides, natural killer T cell-activating lipids from bacteria and fungi

S Burugupalli, CF Almeida, DGM Smith, S Shah… - Chemical …, 2020 - pubs.rsc.org
… isolated from the pathogenic fungus Aspergillus fumigatus, … the molecular basis for NKT
cell recognition of this class of … these α-glucosyl and α-glucuronosyl diacylglycerol lipids but …

Invariant natural killer T cells: front line fighters in the war against pathogenic microbes

CM Crosby, M Kronenberg - Immunogenetics, 2016 - Springer
… The biochemical basis for the recognition of the cholesterol-containing antigens is much
less well defined than it is for the glycosphingolipids and glycosylated diacylglycerol antigens. …

Type I natural killer T cells as key regulators of the immune response to infectious diseases

NMS Gálvez, K Bohmwald, GA Pacheco… - Clinical Microbiology …, 2021 - Am Soc Microbiol
… for antigen recognition of the T cell receptor (TCR) and the B … The first one is a glucose-linked
diacylglycerol (named Glc-… this pathogen and promote a T H 1-polarized T cell response …

Molecular recognition of microbial lipid-based antigens by T cells

S Gras, I Van Rhijn, A Shahine, J Le Nours - Cellular and Molecular Life …, 2018 - Springer
recognition by T cells of pathogen-derived peptidic antigens that … antigen-presenting molecules
can serve as antigens, and be … c Superposition of mCD1d presenting the diacylglycerol

[HTML][HTML] NKT cells contribute to the control of microbial infections

S Vogt, J Mattner - Frontiers in cellular and infection microbiology, 2021 - frontiersin.org
… like) T lymphocytes such as natural killer T (NKT) cells play a … Other bacterial NKT cell antigens
are diacylglycerols (DAGs) … -growing, non-pathogenic bacterial species usually detected …

[HTML][HTML] Activation of invariant natural killer T cells stimulated with microbial α-mannosyl glycolipids

M Shimamura, M Yamamura, T Nabeshima, N Kitano… - Scientific reports, 2017 - nature.com
… to α-GalCer are also recognized by iNKT cells in a CD1-dependent … diacylglycerol from
Borrelia burgdorferi 6 and α-glucosyl … receptors (PRRs) for pathogen-associated molecular …

[HTML][HTML] Enterogenous bacterial glycolipids are required for the generation of natural killer T cells mediated liver injury

…, R Xue, L Bai, Z Chen, L Li, K Iwabuchi, T Uede… - Scientific Reports, 2016 - nature.com
cells and intestinal bacterial glycolipids in liver disorders remained unclear. We found that, in
sharp contrast to specific pathogen-… T cells, NKT cells recognize glycolipid antigens that are …

Glycolipid antigen recognition by invariant natural killer T cells and its role in homeostasis and antimicrobial responses

K Hayashizaki, Y Kamii, Y Kinjo - Frontiers in Immunology, 2024 - frontiersin.org
Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria. Nat Immunol.
(2006) … Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive …

[HTML][HTML] Cross talk between natural killer T and dendritic cells and its impact on T cell responses in infections

L Zhao, X Yang - Frontiers in Immunology, 2022 - frontiersin.org
… Unlike conventional T cells, NKT cells recognize glycol- and … Diacylglycerols (DAGs) are
another type of bacterial … 1 NKT cells and inhibition of pathogenic autoreactive CD4 T cells (76, …