GM3 Induces Terminal Differentiation of Leukemic Cells

CH Kim, CH Kim - GM3 Signaling, 2020 - Springer
… , an acute promyelocytic leukemia (APL… differentiation induction by retinoic acid. Decreased
content of glycosphingolipids and granulocytic differentiation by neolacto series gangliosides

Galectins

CH Kim - Glycobiology of Innate Immunology, 2022 - Springer
… the lacto- and neolacto-series GSLs and gangliosides. Lac-N… with the core components of
neolacto-series and lacto-series … -3 expression induces the migrative potentials of myeloid

Gangliosides and Tumor-Associated Ganglioside (TAG) Modulate Receptor-Tyrosine Kinases (RTKs)

CH Kim, CH Kim - Ganglioside Biochemistry, 2020 - Springer
… derivatives such as ganglio-, globo-, and neolacto-series is accumulated in the cells. In fact,
… Some gangliosides inhibit both T and B cell functions and thus ganglioside-induced T cells …

[HTML][HTML] A saccharide primer method as a novel tool for glycomics

T Sato - Glycoforum, 2020 - glycoforum.gr.jp
… , ie, gangliosides, globo-series glycolipids, and neolacto-series glycolipids are … Human
promyelocytic leukemia cell line HL-60 is capable of differentiating to monocytic or granulocytic

Biological roles of aberrantly expressed glycosphingolipids and related enzymes in human cancer development and progression

D Zhuo, X Li, F Guan - Frontiers in physiology, 2018 - frontiersin.org
ganglioside NeuAcGM3 is usually present in normal humanHuman chronic myelogenous
leukemia (CML) K562 cells … The neolacto-series GSL P1 was found to be expressed on both …

Genetic loss of neolacto-series glycosphingolipid (nsGSL) regulator SPPL3 in tumor cells diminishes NK cell activation but does not affect the killing capacity of γδ T …

A Pappot - 2024 - studenttheses.uu.nl
… levels on tumor cells cause a decreased cytotoxicity of CD8 … , chronic lymphocytic leukemia,
acute myeloid leukemia and … To measure nsGSLs and gangliosides on NALM6 cells, GSL …

Regulation of growth factor receptors by glycosphingolipids

S Hakomori, K Handa - Glycosignals in Cancer: Mechanisms of Malignant …, 2016 - Springer
… The findings of the 1980 studies suggested that the N-acetyl group of sialosyl residue and
the N-fatty acyl group of ceramide moiety of gangliosides may cause modification of essential …

[PDF][PDF] Cell-and tissue-specific glycosylation in human stem cell models of development

HE Grace - 2018 - getd.libs.uga.edu
… In neural cultures generated from induced pluripotent stems … the major human GSL classes:
gangliosides, globosides, and … N-glycans and Lacto-/NeoLacto series GSLs can be further …

[HTML][HTML] Pathophysiological roles and applications of glycosphingolipids in the diagnosis and treatment of cancer diseases

X Jin, GY Yang - Progress in Lipid Research, 2023 - Elsevier
… Ganglio-, globo-, isoglobo-, lacto-, and neolacto-series GSLs are predominant in vertebrates…
human tumor cells and can specifically bind to the B subunit of Shiga toxin (STxB), inducing

CHAPTER TEN GANGLIOSIDES AND AUTOIMMUNITY KENAN DEMİR AND SELİM GÖRGÜN

K DEMİR - Human Autoimmunity and Associated Diseases, 2021 - books.google.com
… -type gangliosides (Ang et al. 1999; Li et al. 2003; Kolter 2012; Li 2012). Ganglio, gala, lacto,
and neolacto series are the most common gangliosides … Although gangliosides can induce