The impact of intrauterine growth restriction and prematurity on nephron endowment
MR Sutherland, MJ Black - Nature Reviews Nephrology, 2023 - nature.com
… renal filtration surface area, and therefore diminished renal … susceptibility to the later
development of kidney disease. … capillary growth compared with that of unventilated control sheep …
development of kidney disease. … capillary growth compared with that of unventilated control sheep …
Renal morphology and glomerular capillarisation in young adult sheep born moderately preterm
MR Sutherland, W Malik, VB Nguyen, V Tran… - … Origins of Health and …, 2021 - cambridge.org
… length, surface area and total renal filtration surface area in the … length and surface area,
and the morphology of the kidneys, in … on nephron endowment in the preterm baboon kidney. …
and the morphology of the kidneys, in … on nephron endowment in the preterm baboon kidney. …
[PDF][PDF] The effects of preterm birth and intrauterine growth restriction on kidney development and renal function in the neonate
D Vojisavljevic - 2016 - scholar.archive.org
… reduced total renal filtration surface area when compared to … kidney, which likely reflects a
reduced nephron endowment. … on glomerular capillary growth in the neonatal lamb kidney. J …
reduced nephron endowment. … on glomerular capillary growth in the neonatal lamb kidney. J …
Preterm birth and ventilation decrease surface density of glomerular capillaries in lambs, regardless of postnatal respiratory support mode
E Staub, MJ Dahl, C Yost, S Bowen, T Aoki, A Blair… - Pediatric …, 2017 - nature.com
… , intrauterine and extrauterine growth restriction, and fluid … in sheep (~120 d gestation)
decreases nephron endowment (… and surface area, and reduced total renal filtration surface area. …
decreases nephron endowment (… and surface area, and reduced total renal filtration surface area. …
Structural and functional changes in the kidney caused by adverse fetal and neonatal environments
M Awazu - Molecular Biology Reports, 2022 - Springer
… growth restriction (IUGR), the following … development was reported to be altered in preterm
sheep. Thus glomerular capillary length, surface area, and total kidney filtration surface area …
sheep. Thus glomerular capillary length, surface area, and total kidney filtration surface area …
Physiology and pathophysiology of compensatory adaptations of a solitary functioning kidney
Z McArdle, MF Schreuder, KM Moritz… - Frontiers in …, 2020 - frontiersin.org
… and an increase in single nephron glomerular filtration rate (… suggest that the total nephron
endowment in congenital SFK … In sheep with congenital SFK, the renal responses to systemic …
endowment in congenital SFK … In sheep with congenital SFK, the renal responses to systemic …
[HTML][HTML] Low nephron endowment increases susceptibility to renal stress and chronic kidney disease
… the single-nephron glomerular filtration rate (GFR). These … While glomerular surface area
increased between 2 and 6 … long-term renal adverse effects following neonatal AKI in the …
increased between 2 and 6 … long-term renal adverse effects following neonatal AKI in the …
Nephron number, hypertension, and CKD: physiological and genetic insight from humans and animal models
X Wang, MR Garrett - Physiological Genomics, 2017 - journals.physiology.org
… Fetal nephrectomy in the sheep resulted in the remaining kidney exhibiting a 45% increase
in nephron endowment, … born very premature and after intrauterine growth retardation. J Am …
in nephron endowment, … born very premature and after intrauterine growth retardation. J Am …
The effect of the in utero environment on nephrogenesis and renal function
KM Moritz - Kidney Development, Disease, Repair and …, 2016 - Elsevier
… causes growth restriction and results in decreased kidney … to increase filtration surface
area [137]. This compensatory … in fetal sheep kidneys at mid-gestation after global nutrient …
area [137]. This compensatory … in fetal sheep kidneys at mid-gestation after global nutrient …
Programming of renal development and chronic disease in adult life
ER Lumbers, Y Kandasamy, SJ Delforce… - Frontiers in …, 2020 - frontiersin.org
… between 90 and 120 mL/min/1.73 m 2 body surface area. … Thus, oligonephropathy caused
by fetal growth restriction or in … in the development of hypertension in young sheep whose …
by fetal growth restriction or in … in the development of hypertension in young sheep whose …