Neurobehavioral, neurochemical and synaptic plasticity perturbations during postnatal life of rats exposed to chloroquine in-utero
OJ Olajide, ZO Alliy, DO Ojo, OO Osinubi… - Neurotoxicology and …, 2021 - Elsevier
Despite reports that quinoline antimalarials including chloroquine (Chq) exhibit idiosyncratic
neuropsychiatric effects even at low doses, the drug continues to be in widespread use
during pregnancy. Surprisingly, very few studies have examined the potential neurotoxic
action of Chq exposure at different points of gestation or how this phenomenon may affect
neurophysiological well-being in later life. We therefore studied behavior, and the
expression of specific genes and neurochemicals modulating crucial neural processes in …
neuropsychiatric effects even at low doses, the drug continues to be in widespread use
during pregnancy. Surprisingly, very few studies have examined the potential neurotoxic
action of Chq exposure at different points of gestation or how this phenomenon may affect
neurophysiological well-being in later life. We therefore studied behavior, and the
expression of specific genes and neurochemicals modulating crucial neural processes in …
以上显示的是最相近的搜索结果。 查看全部搜索结果