Advanced functional materials and cell‐based therapies for the treatment of ischemic stroke and postischemic stroke effects
C Tapeinos, A Larrañaga, F Tomatis… - Advanced Functional …, 2020 - Wiley Online Library
… that occurs in the neurovascular unit after an acute ischemic … , oxidative stress, and
apoptosis,70 while the use of VEGF … conditions, such as the overproduction of thrombin, MMP-9,88 …
apoptosis,70 while the use of VEGF … conditions, such as the overproduction of thrombin, MMP-9,88 …
Novel approaches for the delivery of therapeutics in ischemic stroke
… in the concept of treating neurovascular units (NVUs) as a … enhances the expression of VEGF
specifically in brain tissue … sequentially after being degraded by thrombin. In this approach, …
specifically in brain tissue … sequentially after being degraded by thrombin. In this approach, …
A review on cellular and molecular mechanisms linked to the development of diabetes complications
RA Babel, MP Dandekar - Current Diabetes Reviews, 2021 - ingentaconnect.com
… to the augmentation of oxidative stress like the activation of … the coagulation system, thrombin
formation, fibrinolysis, platelet … like vascular endothelial growth factor (VEGF). This leads to …
formation, fibrinolysis, platelet … like vascular endothelial growth factor (VEGF). This leads to …
The development of drug delivery systems for efficient intracranial hemorrhage therapy
W Yu, B Liu, L Zhou, E Gong, C Che… - Advanced …, 2023 - Wiley Online Library
… , thrombin, and so on, which will cause a series of damage to … endothelial growth factor (VEGF)
and matrix metallopeptidase… showed the protection of neurovascular units in rats with SAH…
and matrix metallopeptidase… showed the protection of neurovascular units in rats with SAH…
[HTML][HTML] Adverse effects of anabolic-androgenic steroids: a literature review
GD Albano, F Amico, G Cocimano, A Liberto… - Healthcare, 2021 - mdpi.com
… , especially long-term toxicity involving the cardiovascular … effect of physical activity in
diminishing oxidative stress as a … expression of VEGF may play a role in skeletal damage due to …
diminishing oxidative stress as a … expression of VEGF may play a role in skeletal damage due to …
[HTML][HTML] Dl-3-n-butylphthalide reduces neurovascular inflammation and ischemic brain injury in mice
… As early as hours after brain ischemia, increased oxidative stress … leukocytes and
neurovascular unit. We examined the … (A) Flow cytometry analysis of the expression of thrombin …
neurovascular unit. We examined the … (A) Flow cytometry analysis of the expression of thrombin …
Intraventricular hemorrhage and white matter injury in preclinical and clinical studies
O Romantsik, M Bruschettini, D Ley - Neoreviews, 2019 - publications.aap.org
… endothelial growth factor (VEGF) overexpression is induced … the effect of clot-derived factors,
such as thrombin, Hb and its … its cytotoxic and pro-oxidative damage. (79) Therefore, the …
such as thrombin, Hb and its … its cytotoxic and pro-oxidative damage. (79) Therefore, the …
Blood-brain barrier dysfunction in ischemic stroke: targeting tight junctions and transporters for vascular protection
W Abdullahi, D Tripathi… - American Journal of …, 2018 - journals.physiology.org
… relationship implies existence of a “neurovascular unit (NVU).” … with vascular endothelial
growth factor (VEGF) receptor 2. … Using an in vivo animal model, oxidative stress was shown …
growth factor (VEGF) receptor 2. … Using an in vivo animal model, oxidative stress was shown …
[HTML][HTML] Evolution of blood–brain barrier in brain diseases and related systemic nanoscale brain-targeting drug delivery strategies
L Han, C Jiang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
… accumulation of fibrin (ogen), thrombin, plasmin (ogen) and … Oxidative stress and
neuroinflammation induce expression … vascular endothelial growth factor (VEGF); a prominent …
neuroinflammation induce expression … vascular endothelial growth factor (VEGF); a prominent …
Effects of crenolanib, a nonselective inhibitor of PDGFR, in a mouse model of transient middle cerebral artery occlusion
J Wang, X Fu, D Zhang, L Yu, Z Lu, Y Gao, X Liu, J Man… - Neuroscience, 2017 - Elsevier
… Briefly, we deeply anesthetized mice with an overdose of … number of proliferative vessels and
levels of VEGF, SDF-1, and MCP-1 … of the neurovascular unit and play essential roles in the …
levels of VEGF, SDF-1, and MCP-1 … of the neurovascular unit and play essential roles in the …