Neutrophils in the tumor microenvironment

DR Powell, A Huttenlocher - Trends in immunology, 2016 - cell.com
… Here we review the mechanisms that regulate neutrophil … the tumor microenvironment. We
discuss the current understanding as to how neutrophils alter the tumor microenvironment to …

Neutrophils in the tumor microenvironment

L Wu, S Saxena, RK Singh - Tumor Microenvironment: Hematopoietic …, 2020 - Springer
… Recent studies demonstrating elevated neutrophil to lymphocyte ratios suggest neutrophil as
… in the neutrophil in the tumor microenvironment, the underlying mechanism(s) of neutrophil

Neutrophils in the tumor microenvironment: trying to heal the wound that cannot heal

KL Singel, BH Segal - Immunological reviews, 2016 - Wiley Online Library
… we will discuss neutrophil biology in the tumor microenvironment in the context … tumor
microenvironment and neutrophil heterogeneity that modulate the interactions between neutrophils

Tumor‐associated macrophages and neutrophils in tumor microenvironment

J Kim, JS Bae - Mediators of inflammation, 2016 - Wiley Online Library
microenvironment. Special attention will be given to the … tumor-associated cells and to
the roles they play in maintenance of the tumor microenvironment and progression of tumors. …

Neutrophil plasticity in the tumor microenvironment

MA Giese, LE Hind… - Blood, The Journal of the …, 2019 - ashpublications.org
… understanding neutrophil biology in the tumor microenvironment. It is clear that neutrophils
… regulation of components of the tissue microenvironment and other immune cells. However, …

Neutrophils as active regulators of the immune system in the tumor microenvironment

ME Shaul, ZG Fridlender - Journal of leukocyte biology, 2017 - academic.oup.com
… to promote tumor growth and neutrophil mobilization [60], to induce the expression of
CXCL8/IL-8 in epithelial cells, which, in turn, recruit neutrophils to the tumor microenvironment and …

Tumor-associated neutrophils as new players in immunosuppressive process of the tumor microenvironment in breast cancer

F Hajizadeh, LA Maleki, M Alexander, MV Mikhailova… - Life sciences, 2021 - Elsevier
… Activated neutrophils form NET in the tumor microenvironment playing a pro-tumor role
during tumor progression [52,53]. It has been reported that the levels of NET in patients' plasma …

Targeting the tumor microenvironment: a close up of tumor-associated macrophages and neutrophils

M Russo, C Nastasi - Frontiers in Oncology, 2022 - frontiersin.org
… Resistance to cancer treatment can be intrinsic to the tumor cells, but it is often conferred by
non-malignant ones that make up the tumor microenvironment (TME). The importance of the …

Neutrophil elastase in the tumor microenvironment

I Lerman, SR Hammes - Steroids, 2018 - Elsevier
… the role of neutrophil elastase in … neutrophil elastase may facilitate primary tumor growth
and secondary organ metastasis. Importantly, we conclude with a brief discussion of neutrophil

The recruitment of neutrophils to the tumor microenvironment is regulated by multiple mediators

S SenGupta, LE Hein, CA Parent - Frontiers in immunology, 2021 - frontiersin.org
… functions, neutrophils are emerging as one of the key tumor-… Neutrophil recruitment to the
tumor microenvironment (TME) … how neutrophils integrate these signals to reach and invade …