Anticancer agents incorporating the Nacylhydrazone scaffold: Progress from 2017 to present

AE Kassab - Archiv der Pharmazie, 2023 - Wiley Online Library
potent anticancer agents acting via different mechanisms. An updated summary of the anticancer
activity of N-acylhydrazone derivatives … In the N-acylhydrazone derivatives, the pyridine

[HTML][HTML] Acylhydrazones and their biological activity: a review

LI Socea, SF Barbuceanu, EM Pahontu, AC Dumitru… - Molecules, 2022 - mdpi.com
… A number of derivatives containing the acylhydrazone moiety are … containing the acylhydrazone
scaffold are shown in Figure 1. … the literature describing the acylhydrazone moiety as an …

[HTML][HTML] Cytotoxic activity and docking studies of 2-arenoxybenzaldehyde N-acyl hydrazone and 1, 3, 4-oxadiazole derivatives against various cancer cell lines

E Aydın, AM Şentürk, HB Küçük, M Güzel - Molecules, 2022 - mdpi.com
… and oxadiazole derivatives have promising anticancer effects, … kinase 2 to investigate their
anticancer activity on breast cancer, … We compared our results with the often-used anticancer

[HTML][HTML] Synthesis and evaluation of new benzimidazole derivatives with hydrazone moiety as anticancer agents

U Acar Çevik, BN Sağlık, CM Ardıç… - Turkish Journal of …, 2018 - degruyter.com
… of new chemical entities as potent anticancer agents. … thiophen/furan-2-yl-methylene)
benzohydrazide derivatives were … of novel acylhydrazone derivatives as potential antitumor

Synthesis and anticancer activity of novel hydrazone linkage-based aryl sulfonate derivatives as apoptosis inducers

S Şenkardeş, M İhsan Han, M Gürboğa… - Medicinal Chemistry …, 2022 - Springer
In the present study, the various 28 hybrid molecules containing hydrazone and sulfonate
moieties were synthesized and characterized by FTIR, 1 H-NMR, 13 C-NMR spectroscopy and …

Promising Dual Anticancer and Antimetastatic Action by a Cu (II) Complex Derived from Acylhydrazone on Human Osteosarcoma Models

L Santa Maria de la Parra, AIB Romo… - Inorganic …, 2024 - ACS Publications
anticancer and antimetastatic drug. The multiaction of a new Cu(II) complex derived from
acylhydrazone … A new type of anticancer drug known as “metallodrugs” is primarily used to treat …

[HTML][HTML] New benzenesulphonohydrazide derivatives as potential antitumour agents

Ł Popiołek, M Gawrońska‑Grzywacz… - Oncology …, 2020 - spandidos-publications.com
new benzenesulphonohydrazide derivatives (1‑9) were synthesized, and the chemical
structures of the obtained compounds were confirmed by spectral analysis methods, including IR, …

Synthesis and Biological Activity of N-Acylhydrazones

ER Belyaeva, YV Myasoedova, NM Ishmuratova… - Russian Journal of …, 2022 - Springer
… Synthesis of hydrazone derivatives of xanthine. Acylhydrazones were synthesized based
on pyridine carboxylic acid hydrazides and furoxanyl, and their activity against the M. …

[PDF][PDF] Synthesis of substituted aromatic heterocyclic sulfonyl hydrazone compounds and in vitro anti-hepatoma activity: preliminary results.

DC Wei, D CAI, Y PAN, H WANG, WJ XU… - European Review for …, 2018 - europeanreview.org
… of diverse hydrazone derivatives and to explore the potent antitumor activities. MATERIALS
New class of potent antitumor acylhydrazone derivatives containing furan. Eur J Med Chem …

[HTML][HTML] Synthesis and in vitro anticancer activity of novel dehydroabietic acid-based acylhydrazones

FY Li, X Wang, WG Duan, GS Lin - Molecules, 2017 - mdpi.com
potent anticancer activities, a series of dehydroabietic acid (DHA) derivatives bearing an
acylhydrazone … In addition, displacement of benzene with pyridine appeared to have a positive …