… Here we report on GWAS utilizing baseline parameters of renal function, glomerular … in the
Chronic Renal Insufficiency Cohort (CRIC) study [38], a study of adult patients with CKD. Data …

… That the associated variant may operate directly through effects on kidney function is further
… no relationships between the variant and kidney disease risk factors such as diabetes and …

… glycoproteins become deposited in the chronically-damaged kidney; the area of fibrotic
interstitium affected is closely associated with both renal function and long-term renal prognosis. …

… , we identified new potential target genes for CKD. With respect … variants associated
with MANBA expression in the kidney … Impaired kidney function is associated with a 3- to 5-fold …

… In summary, ~82% (348 loci) of the 424 identified eGFRcrea loci were validated by … relevant
for kidney function. Our results underscore the value of eGFRcys to kidney function GWAS, …

… Lead SNPs in each genetic loci associated with kidney function-related traits. … transplantation
and drug metabolism in end-stage renal disease patients [30,31]. C17orf82 was previously …

… CKD progression, we performed a genome–wide association study among participants in
the Chronic Renal Insufficiency … biologic pathways related to level of renal function. However, …

… We did not observe any renal functional or histological abnormalities in Ksp-Cre and Dab2
flox/+ mice at baseline. Next, we subjected these animals to folic-acid-induced acute and …

… signals impact on kidney function, we expand the COGENT-Kidney Consortium in this …
With these data, we identify novel loci and distinct associations for kidney function, assess …

… among other loci, associated with kidney function in European … gene has also found to be
associated with renal cancer [8]. … End-stage renal disease patients carrying the variant allele of …