Reprogramming the local lymph node microenvironment promotes tolerance that is systemic and antigen specific
… In a mouse MS model, intra-LN introduction of encapsulated … we used direct lymph node
(LN) delivery as a tool to isolate … MPs, to probe the local tissue- and cell-level changes in LNs …
(LN) delivery as a tool to isolate … MPs, to probe the local tissue- and cell-level changes in LNs …
[HTML][HTML] Towards the development of human immune-system-on-a-chip platforms
… decades provided convenient models for immunologists, and have … the lymph draining from
peripheral tissues and carrying tissue-… Lymph node structure and an example of an ex vivo …
peripheral tissues and carrying tissue-… Lymph node structure and an example of an ex vivo …
Tertiary lymphoid structures in cancer–considerations for patient prognosis
L Munoz-Erazo, JL Rhodes, VC Marion… - … & molecular immunology, 2020 - nature.com
… such as lymph nodes and can contain B-cell follicles and … Model of the composition of a
tertiary lymphoid structure. … TLS in broad regions in peritumoral tissue up to 7 mm from the …
tertiary lymphoid structure. … TLS in broad regions in peritumoral tissue up to 7 mm from the …
The internal conduit system of the swine inverted lymph node
L Dubreil, M Ledevin, C Hervet, D Menard… - … in immunology, 2022 - frontiersin.org
… Using up to date microscopy tools, we described the … cell-associated antigens are drained
from peripheral tissues to … We thus propose here a refined model of the lymphatic and blood …
from peripheral tissues to … We thus propose here a refined model of the lymphatic and blood …
Ectopic lymphoid follicles: inducible centres for generating antigen‐specific immune responses within tissues
GW Jones, SA Jones - Immunology, 2016 - Wiley Online Library
… Lymph nodes are strategically located throughout the body … cells as they are trafficking from
peripheral organs and tissue. … models of melanoma and lung carcinoma, the development of …
peripheral organs and tissue. … models of melanoma and lung carcinoma, the development of …
Modulation of immunity by lymphatic dysfunction in lymphedema
… (20), lymph node transplantation (21) and other regional tissue … + T cells were activated in
skin-draining lymph nodes and … prevented lymphedema in the mouse tail model employed in …
skin-draining lymph nodes and … prevented lymphedema in the mouse tail model employed in …
Lymph node conduits transport virions for rapid T cell activation
GV Reynoso, AS Weisberg, JP Shannon… - … immunology, 2019 - nature.com
… Current models fail to explain how virus-infected cells rapidly … minutes of deposition into
peripheral tissues 10 . Virions present … Thus, viruses serve as the perfect tool to uncover a …
peripheral tissues 10 . Virions present … Thus, viruses serve as the perfect tool to uncover a …
Detection of PD-L1–Expressing Myeloid Cell Clusters in the Hyaluronan-Enriched Stroma in Tumor Tissue and Tumor-Draining Lymph Nodes
PR Dominguez-Gutierrez, EP Kwenda… - … of Immunology, 2022 - journals.aai.org
… lymph nodes (TDLNs), but not in distant lymph nodes (LNs). Our results support the idea
that HA produced by stroma and tumor cells … In addition to the bladder tumor model, we also …
that HA produced by stroma and tumor cells … In addition to the bladder tumor model, we also …
Tissues, not blood, are where immune cells function
DL Farber - Nature, 2021 - nature.com
… tissue (see ‘Human tissues for immunology’). In surgeries from tonsillectomies to tumour
removals, lymph nodes … gut tissues that are rich in immune cells and lymph nodes associated …
removals, lymph nodes … gut tissues that are rich in immune cells and lymph nodes associated …
A short field guide to fibroblast function in immunity
MB Buechler, SJ Turley - Seminars in immunology, 2018 - Elsevier
… lymph nodes (LN), spleen and Peyer’s Patches, are tissues … This model aims to highlight
the tripartite manner in which … to a dearth of genetic tools so we endeavored to acknowledge …
the tripartite manner in which … to a dearth of genetic tools so we endeavored to acknowledge …