Niche and local geography shape the pangenome of wastewater-and livestock-associated Enterobacteriaceae
LP Shaw, KK Chau, J Kavanagh, M AbuOun… - Science …, 2021 - science.org
Escherichia coli and other Enterobacteriaceae are diverse species with “open”
pangenomes, where genes move intra-and interspecies via horizontal gene transfer.
However, most analyses focus on clinical isolates. The pangenome dynamics of natural
populations remain understudied, despite their suggested role as reservoirs for antimicrobial
resistance (AMR) genes. Here, we analyze near-complete genomes for 827
Enterobacteriaceae (553 Escherichia and 274 non-Escherichia spp.) with 2292 circularized …
pangenomes, where genes move intra-and interspecies via horizontal gene transfer.
However, most analyses focus on clinical isolates. The pangenome dynamics of natural
populations remain understudied, despite their suggested role as reservoirs for antimicrobial
resistance (AMR) genes. Here, we analyze near-complete genomes for 827
Enterobacteriaceae (553 Escherichia and 274 non-Escherichia spp.) with 2292 circularized …
[PDF][PDF] Niche and local geography shape the pangenome of wastewater-and livestock-associated Enterobacteriaceae
SJ Hoosdally, R Sebra, HO Brett - centaur.reading.ac.uk
Escherichia coli and other Enterobacteriaceae are diverse species with “open”
pangenomes, where genes move intra-and interspecies via horizontal gene transfer.
However, most analyses focus on clinical isolates. The pangenome dynamics of natural
populations remain understudied, despite their suggested role as reservoirs for antimicrobial
resistance (AMR) genes. Here, we analyze near-complete genomes for 827
Enterobacteriaceae (553 Escherichia and 274 non-Escherichia spp.) with 2292 circularized …
pangenomes, where genes move intra-and interspecies via horizontal gene transfer.
However, most analyses focus on clinical isolates. The pangenome dynamics of natural
populations remain understudied, despite their suggested role as reservoirs for antimicrobial
resistance (AMR) genes. Here, we analyze near-complete genomes for 827
Enterobacteriaceae (553 Escherichia and 274 non-Escherichia spp.) with 2292 circularized …
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