Neurobiological mechanisms of nicotine reward and aversion

L Wills, JL Ables, KM Braunscheidel, SPB Caligiuri… - Pharmacological …, 2022 - ASPET
… These aversion-related brain sites regulate nicotine … sites increases vulnerability to tobacco
dependence and smoking-… -level mechanisms through which nicotine elicits reward and …

[HTML][HTML] Individual variations in the mechanisms of nicotine seeking: a key for research on nicotine dependence

V Garcia-Rivas, N Cannella… - …, 2017 - nature.com
… the mechanisms that underlie tobacco dependence, in which … In search for the mechanisms
of individual vulnerability to … their underlying neurobiological mechanisms using preclinical …

Mechanisms of nicotine addiction

MR Picciotto, PJ Kenny - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
vulnerability to tobacco dependence and smoking-… aversive properties of nicotine that
control the quantities of the drug consumed and in the development of tobacco dependence

Addiction‐related neuroadaptations following chronic nicotine exposure

L Wills, PJ Kenny - Journal of neurochemistry, 2021 - Wiley Online Library
… the “set-point” for nicotine aversion and control nicotine intake. … of tobacco dependence that
will facilitate smoking cessation. … of nicotine likely contributes to the increased vulnerability to …

Neurobiology and Mechanisms of Nicotine Addiction

HP Gogineni, DPL Sachs, DH Brunzell - Tobacco Dependence: A …, 2023 - Springer
… The α3β4* are primarily implicated in nicotine aversion and … Understanding the neurobiological
mechanisms engaged by … Understanding genetic vulnerability to tobacco dependence

[HTML][HTML] Multifactorial etiology of adolescent nicotine addiction: a review of the neurobiology of nicotine addiction and its implications for smoking cessation …

SD Mahajan, GG Homish, A Quisenberry - Frontiers in public health, 2021 - frontiersin.org
… of nicotine may be an important factor in vulnerability to … tobacco dependence in the adolescent
using the Fagerström test for … lower withdrawal symptoms and aversive effects (60, 102). …

Neurobiological considerations for tobacco use disorder

M Chawla, KA Garrison - Current behavioral neuroscience reports, 2018 - Springer
… highlights new evidence in neurobiology of nicotine’s effects … been shown to increase
vulnerability to tobacco smoking [18]. … Novel approaches for the treatment of tobacco dependence

Not all smokers appear to seek nicotine for the same reasons: implications for preclinical research in nicotine dependence

V Garcia‐Rivas, V Deroche‐Gamonet - Addiction Biology, 2019 - Wiley Online Library
tobacco addiction have explored the mechanisms of nicotine … Factors other than the balance
of nicotine reward and aversion … has explored the mechanisms of these vulnerabilities, this …

Molecular and neuronal mechanisms underlying the effects of adolescent nicotine exposure on anxiety and mood disorders

SR Laviolette - Neuropharmacology, 2021 - Elsevier
… The nature of tobacco dependence has changed … and aversive stimulus properties of acute
nicotine and chronic … between smoking behaviours and increased vulnerability for mood and …

Enhanced vulnerability to tobacco use in persons with diabetes: A behavioral and neurobiological framework

LE O'Dell, A Nazarian - Progress in Neuro-Psychopharmacology and …, 2016 - Elsevier
nicotine are enhanced in rodent models of type 1 and type 2 diabetes. We also provide a
framework of neurobiological mechanisms … Diabetes and tobacco abuse are complex problems …