[HTML][HTML] Nitric oxide (NO) and NO synthases (NOS)-based targeted therapy for colon cancer
… NO-donating NSAIDs (NO-NSAIDs) possess a traditional … modulate the NO-releasing rate
and targeting capability of NO-… has the risk of the rapid bursting of toxic agents, such as nitrates…
and targeting capability of NO-… has the risk of the rapid bursting of toxic agents, such as nitrates…
Nitroxyl (HNO): a possible strategy for fighting cancer
… Critical thiols that control cancer cellular functions might be … the heme-iron-catalyzed reduction
of nitrite with H2S [11]. This … -NSAIDs) is one important strategy to minimize NSAIDs side …
of nitrite with H2S [11]. This … -NSAIDs) is one important strategy to minimize NSAIDs side …
The latest advances in the discovery of nitric oxide hybrid drug compounds
RAM Serafim, FG Pernichelle… - Expert Opinion on Drug …, 2017 - Taylor & Francis
… , ester nitrate and S-nitrosothiol are the main functional groups … This study showed that this
new NSAIDs/NO-donor hybrid has … , the treatment in vivo with complex non-bound NO did not …
new NSAIDs/NO-donor hybrid has … , the treatment in vivo with complex non-bound NO did not …
[HTML][HTML] Reconsidering the role of cyclooxygenase inhibition in the chemotherapeutic value of NO-releasing aspirins for lung cancer
A Martin-Martin, A Rivera-Dictter, M Muñoz-Uribe… - Molecules, 2019 - mdpi.com
… -aspirins has been queried. Moreover, different isomers exhibit … , NO-NSAIDs may also
have roles in cancer treatment or … both in vivo and in vitro models of leukemia, ovarian cancer, …
have roles in cancer treatment or … both in vivo and in vitro models of leukemia, ovarian cancer, …
Novel nitric oxide donor, nitrated phenylbutyrate, induces cell death of human pancreatic cancer cells and suppresses tumor growth of cancer xenografts
T Beppu, K Nishi, S Imoto, W Araki… - Oncology …, 2022 - spandidos-publications.com
… cancer, NPB based on chlorambucil, a PB analogue, was synthesized and the effects in vitro
and in vivo … It is known that a part of nitrite ions released from the NO-donor compound are …
and in vivo … It is known that a part of nitrite ions released from the NO-donor compound are …
Prodrugs Bioactivated to Quinones Target NF-κB and Multiple Protein Networks: Identification of the Quinonome
EN Pierce, SC Piyankarage, T Dunlap… - Chemical research in …, 2016 - ACS Publications
… NO-donating NSAID prodrugs (NO-NSAIDs) have been the focus of extensive clinical and
preclinical studies in inflammation and cancer chemoprevention and therapy: a … functions and …
preclinical studies in inflammation and cancer chemoprevention and therapy: a … functions and …
Prospects of NSAIDs administration as double-edged agents against endometrial cancer and pathological species of the uterine microbiome
O Kuźmycz, P Stączek - Cancer biology & therapy, 2020 - Taylor & Francis
… effective approach in cancer prevention and treatment supporting, … Bacterial features and
balanced microbiome are relatively … NO-NSAIDs and cGMP PDE were reported to have positive …
balanced microbiome are relatively … NO-NSAIDs and cGMP PDE were reported to have positive …
[HTML][HTML] … of fac-[Re(CO)3(phen)(aspirin)], fac-[Re(CO)3(phen)(indomethacin)] and Their Original Counterparts against Ishikawa and HEC-1A Endometrial Cancer …
O Kuźmycz, A Kowalczyk, P Stączek - International Journal of Molecular …, 2022 - mdpi.com
… the context of cancer prevention and supportive treatment, as … capabilities and can trigger
oxidative stress-induced cancer … , such as: NO-NSAIDs (hybrid nitrate NSAIDs), cGMP PDE (…
oxidative stress-induced cancer … , such as: NO-NSAIDs (hybrid nitrate NSAIDs), cGMP PDE (…
Soluble guanylyl cyclase is a critical regulator of migraine-associated pain
… were potentiated by NO generated by the NO-donor DETA/NO. Bioavailability … vivo. A final
comparison of VL-102 with YC-1, in the presence and absence of a related NO-donor, DEA/NO…
comparison of VL-102 with YC-1, in the presence and absence of a related NO-donor, DEA/NO…
Modulation of Estrogen Oxidative Metabolism by Botanicals (Hops and Licorice) Used for Women's Health
S Wang - 2017 - indigo.uic.edu
… effects on breast cancer prevention. Future studies are needed to test the botanicals in vivo
and … LicA is also a Michael acceptor, but does not have the self-cyclizing capability. LicA has …
and … LicA is also a Michael acceptor, but does not have the self-cyclizing capability. LicA has …