… into the target enzyme. In this review, the phylogenetic distribution of nickel enzymes will be
… reactions spanning over 1.5 V, while in nonredox enzymes, Ni(II) is used as a Lewis acid. …

… These enzymes often possess unique metallocofactors, … Nickel enzymes, present in
archaea, bacteria, plants and primitive eukaryotes are divided into redox and non‐redox enzymes …

… For instance, methyl-CoM reductase (MCR), the rate-limiting enzyme in methanogenesis …
-halide, alkyl, and aryl complexes typically exhibit nickel(I) centers, supported by non-redox-…

… of nickel-dependent enzymes and then summarizes theoretical studies on the reaction
mechanisms of these enzymes, … studies on nickel enzymes by quantum chemical calculations. …

… some of the nickel-binding factors that sustain nickel enzyme production in … We begin with
the metallophores and the import machinery that mediate nickel ion … Nonredox nickel enzymes …

… nickel ions and describes nickel-dependent enzymatic … respond to nickel ion concentrations
by synthesizing nickel-… of a non-redox metal ion in an essential enzyme by nickel. (d…

… The enzymes and complexes discussed in this review have been classified based on the …
, copper, nickel, and manganese. The main points of discussion focus on enzyme structure and …

… LarC incorporates nickel to form a C–Ni and two S–Ni bonds, … Depending on the source of
the enzyme, LarEs either catalyze … enzyme that cytidinylylates its substrate, adds nickel, then …

… mononucleotide, is covalently tethered to Lys184 of the enzyme and serves as a tridentate
ligand to nickel. This molecule, with nickel bound in nearly planar geometry to the pyridinium …

… of nickel chaperones in enzyme maturation and activation is being extensively investigated,
but … enzymes – urease and Ni, Fe hydrogenase both of which require a common nickel-…