[HTML][HTML] Fer1l5, a dysferlin homologue present in vesicles and involved in c2c12 myoblast fusion and membrane repair

R Usha Kalyani, K Perinbam, P Jeyanthi, NA Al-Dhabi… - Biology, 2020 - mdpi.com
myoferlin have been well characterized in myoblast fusion. … Therefore, we followed the
common protocol as described in … , highlighting that myoblast fusion is not only required during …

Myoferlin, a multifunctional protein in normal cells, has novel and key roles in various cancers

W Zhu, B Zhou, C Zhao, Z Ba, H Xu… - Journal of cellular …, 2019 - Wiley Online Library
… the fusion of two opposed lipid bilayers. Furthermore, myoferlin interacts with EHD2 to regulate
myoblast fusion … kinase receptors requires myoferlin, including VEGFR-2 and Tie-2. Acute …

Mechanisms regulating myoblast fusion: A multilevel interplay

L Lehka, MJ Rędowicz - Seminars in Cell & Developmental Biology, 2020 - Elsevier
… A, Myoblast fusion takes place in two stages: in the first … initial steps of myoblasts fusion
take place normally, but there … of myoferlin is high in myoblasts before initiation of the fusion

Muscle cell communication in development and repair

AR Demonbreun, EM McNally - Current opinion in pharmacology, 2017 - Elsevier
… 1 signaling and ineffective myoblast fusion, myoferlin-null mice exhibit … Myoferlin-null
myofibers reseal more slowly than normal fibers after … Normal myoblast fusion requires myoferlin

Regulation of the myoblast fusion reaction for muscle development, regeneration, and adaptations

DP Millay - Experimental cell research, 2022 - Elsevier
… Not only does myocyte fusion impact the normal biology of skeletal … Indeed, GRAF1 and
myoferlin, have not been shown to … that for myoblast fusion to occur, TGF-β signaling needs to be …

[HTML][HTML] Myoferlin regulates Wnt/β-catenin signaling-mediated skeletal muscle development by stabilizing dishevelled-2 against autophagy

S Han, C Cui, H He, X Shen, Y Chen, Y Wang… - International Journal of …, 2019 - mdpi.com
… This indicated that MyoF is required for … by myoblast fusion to form myotubes, a process
in which MyoF functions in the maturation of myotubes [25]. Our results showed that the normal

An emerging therapeutic approach by targeting myoferlin (MYOF) for malignant tumors

H Gu, Y Peng, Y Chen - Current Topics in Medicinal Chemistry, 2020 - ingentaconnect.com
… The research has uncovered that MYOF is required for insulin-… The structure of MYOF and
functions of MYOF in normal cells. … EHD2 interacts with myoferlin to regulate myoblast fusion. …

Myoferlin, a membrane protein with emerging oncogenic roles

Y Dong, H Kang, H Liu, J Wang, Q Guo… - BioMed Research …, 2019 - Wiley Online Library
… It is important for membrane repair and myoblast fusion. … However, further studies are required
to elucidate the exact role … of MYOF is observed in normal epithelial tissue and low-grade …

Acting on identity: myoblast fusion and the formation of the syncytial muscle fiber

S Deng, M Azevedo, M Baylies - Seminars in cell & developmental biology, 2017 - Elsevier
… on myoblast fusion, the process responsible for the generation of syncytial muscle cells. We
also compare and contrast those genes required for fusion in … proteins, such as Myoferlin

Structure–function analysis of myomaker domains required for myoblast fusion

DP Millay, DG Gamage, ME Quinn… - Proceedings of the …, 2016 - National Acad Sciences
… , which resulted in complete blockade to fusion. To define the functional domains of myomaker
required to direct fusion, we established a heterologous cell–cell fusion system, in which …