… OHdG), a biomarker of mitochondrial DNA (mtDNA) oxidative … showed that leukocyte mtDNA
copy number variation (mtDNA-CN… A novel finding of our study is that mtDNA 8-OHdG was a …

… of efforts was to explore the novel tools for more accurate risk … In the future study, mitochondria
DNA copy variation should to … with coronary artery disease and myocardial infarction in …

… Type 2 diabetes mellitus affects an estimated 1 in 10 … coronary artery disease, the extent of
mitochondrial DNA … sample may serve as novel biomarkers of cardiovascular injury. Future …

… and blood pressure medications (field #6153), type 2 diabetes (T2D, fields #41201, #41202 …
Currently, functional studies for MT-SNVs are not readily available; however, several novel …

… utility of mtDNA as a novel clinical biomarker of CVD risk. … bypass grafting or coronary artery
angioplasty) at baseline. In … of atherosclerosis, cardiac embolism, and small vessel disease. …

… that mitochondrial DNA mutations are associated with heart … been associated with several
muscular and cardiac diseases [… investigated DNA variations in seven mitochondrial hotspot …

… Patients with T2D had significantly lower mtDNA copy … , six mtDNA variants were significantly
associated with mtDNA copy … and novel variants of mtDNA are significantly associated with …

… that contributed to pathogenesis of coronary artery disease. The m.… mitochondria from
a Chinese family carrying the m.15927G>A mutation and a control into mitochondrial DNA (mtDNA)…

… diabetes mellitus, the occurrence of coronary artery disease (CAD) is related to higher mtDNA
… be answered in order to develop novel therapeutics targeting cardiac inflammation. First, it …

… of mitochondrial DNA (mtDNA). G10398A (more ROS), T16189C (impaired response to
ROS) variants of mtDNA were … T2DM [158], and T16189C was also associated with CAD [159]. …