Novel approaches to the management of noneosinophilic asthma
NC Thomson - Therapeutic advances in respiratory disease, 2016 - journals.sagepub.com
… in asthma and assesses clinical trials of licensed drugs, novel … in noneosinophilic asthma
than eosinophilic asthma. Noneosinophilic … is reported in neutrophilic asthma. Neutrophilia in …
than eosinophilic asthma. Noneosinophilic … is reported in neutrophilic asthma. Neutrophilia in …
Latrophilin receptors: novel bronchodilator targets in asthma
… a novel role for latrophilin (LPHN) receptors, finding increased expression on ASMC from
asthmatics, compared with non-asthmatics in … was associated with asthma and with increased …
asthmatics, compared with non-asthmatics in … was associated with asthma and with increased …
A phase IIa proof-of-concept, placebo-controlled, randomized, double-blind, crossover, single-dose clinical trial of a new class of bronchodilator for acute asthma
V Swystun, FHY Green, JH Dennis, E Rampakakis… - Trials, 2018 - Springer
… This study evaluates a novel bronchodilator, S1226, for its efficacy in reversing allergen-…
in subjects with mild, allergic asthma. S1226 is a new class of bronchodilator that is an aerosol/…
in subjects with mild, allergic asthma. S1226 is a new class of bronchodilator that is an aerosol/…
The future of bronchodilation: looking for new classes of bronchodilators
M Cazzola, P Rogliani… - European Respiratory …, 2019 - Eur Respiratory Soc
… the pharmaceutical industry in developing novel bronchodilators. There are several new …
from asthmatic patients [75]. It has been documented that the sputum from asthmatic patients …
from asthmatic patients [75]. It has been documented that the sputum from asthmatic patients …
[HTML][HTML] A novel in vivo system to test bronchodilators
KJ Addison, J Morse, A Robichaud… - Journal of infectious …, 2017 - ncbi.nlm.nih.gov
… Fast acting drugs, such as albuterol, or novel therapeutic treatments for asthma have been
… drugs can be reproducibly tested to advance the development of novel asthma therapeutics. …
… drugs can be reproducibly tested to advance the development of novel asthma therapeutics. …
New and developing non-adrenoreceptor small molecule drugs for the treatment of asthma
NC Thomson - Expert opinion on pharmacotherapy, 2017 - Taylor & Francis
… developing effective novel small molecule drugs for asthma will … and the different phenotypes
and endotypes of asthma. … with symptomatic asthma and a pre-bronchodilator FEV 1 of 60–…
and endotypes of asthma. … with symptomatic asthma and a pre-bronchodilator FEV 1 of 60–…
Transforming growth factor-β1: a novel cause of resistance to bronchodilators in asthma?
MA Wortley, SJ Bonvini - American Journal of Respiratory Cell and …, 2019 - atsjournals.org
… and novel study reveals a mechanism by which resistance to the effects of bronchodilators
may … bronchodilator effects. If future research confirms these findings in the context of severe …
may … bronchodilator effects. If future research confirms these findings in the context of severe …
New avenues for phosphodiesterase inhibitors in asthma
MG Matera, J Ora, F Cavalli, P Rogliani… - Journal of …, 2021 - Taylor & Francis
… asthma mainly for PDE3, PDE4, PDE5 and PDE7. Consequently, drugs that inhibit PDEs may
offer novel … on treatment especially in severe asthma due to their bronchodilator and/or anti-…
offer novel … on treatment especially in severe asthma due to their bronchodilator and/or anti-…
Elucidating novel disease mechanisms in severe asthma
… novel murine models of respiratory infection-induced, severe, steroid-resistant asthma that
… low pre-bronchodilator FEV 1 and high post-bronchodilator response; second cluster with …
… low pre-bronchodilator FEV 1 and high post-bronchodilator response; second cluster with …
Application of nano-and micro-particle-based approaches for selected bronchodilators in management of asthma
S Singh, N Sharma, J Gupta, A Kyada, D Nathiya… - 3 Biotech, 2024 - Springer
… Recently, there have been advancements in the development of novel medications for
asthma therapy. In addition, there have been enhancements in the administration methods of …
asthma therapy. In addition, there have been enhancements in the administration methods of …