Calcium homeostasis in ventricular myocytes of diabetic cardiomyopathy

LT Al Kury - Journal of Diabetes Research, 2020 - Wiley Online Library
… of the disturbances of Ca 2+ transport and the role of main … clusters throughout the
cardiomyocyte leads to a Ca 2+ transient … This was accompanied with activation of p38 kinase, …

SERCA2a: a key protein in the Ca2+ cycle of the heart failure

L Zhihao, N Jingyu, L Lan, S Michael, G Rui, B Xiyun… - Heart failure …, 2020 - Springer
cardiomyocytes, which is used to re-uptake Ca 2+ in the cytoplasm into the sarcoplasmic
reticulum to relax the cardiomyocytes, thereby maintaining Ca 2… stability, nuclear translocation […

The role of nuclear Ca2+ in maintaining neuronal homeostasis and brain health

P Mozolewski, M Jeziorek, CM Schuster… - Journal of cell …, 2021 - journals.biologists.com
… In this Review, we aim to provide a summary of recent findings in the field of nuclear Ca 2+
and strengthen the ‘nuclear calcium hypothesis’ in the context of a regulation of pivotal …

Role of NOD1 in Heart Failure Progression via Regulation of Ca2+ Handling

A Val-Blasco, MJGM Piedras, G Ruiz-Hurtado… - Journal of the american …, 2017 - jacc.org
… primarily on a mechanism called Ca 2+ -induced Ca 2+ release, which is initiated by an
action potential in the cardiomyocytes that fires a small influx of Ca 2+ via sarcolemma L-type …

Transcriptional regulation of intermolecular Ca2+ signaling in hibernating ground squirrel cardiomyocytes: The myocardin–junctophilin axis

L Yang, RC Li, B Xiang, YC Li… - Proceedings of the …, 2021 - National Acad Sciences
… that up-regulate the efficiency of Ca 2+ signaling in cardiomyocytes of hibernating … Nuclear
proteins were extracted from HEK293T cells overexpressing SRF using NE–PER nuclear and …

Regulation of mitochondrial calcium uniporter expression and calcium-dependent cell signaling by lncRNA Tug1 in cardiomyocytes

AJ Trewin, KL Weeks, GD Wadley… - American Journal of …, 2023 - journals.physiology.org
regulates MCU expression in cardiomyocytes, which occurs in part via 83 CaMKII, and that
this has pleiotropic effects on the cardiomyocyte … study is that Ca2+ fluxes or other functional

Nucleus mechanosensing in cardiomyocytes

IL Coscarella, M Landim-Vieira… - International Journal of …, 2023 - mdpi.com
cardiomyocytes. The consistent nature of contraction–relaxation cycles should lead to similar
nuclear responses in cardiomyocytes to provide nuclear … and is regulated by Ca 2+ binding …

Emerging Roles of Neuronal Ca2+ Sensor-1 in Cardiac and Neuronal Tissues: A Mini Review

TY Nakamura, S Nakao… - Frontiers in molecular …, 2019 - frontiersin.org
… is regulated by nuclear Ca 2+ signals. However, the mechanisms underlying nuclear Ca 2+
… to stress tolerance in cardiomyocytes, partly by the activation of Ca 2+ -dependent survival …

Ca2+/Calmodulin-Dependent Protein Kinase II and Androgen Signaling Pathways Modulate MEF2 Activity in Testosterone-Induced Cardiac Myocyte Hypertrophy

J Duran, D Lagos, M Pavez, MF Troncoso… - Frontiers in …, 2017 - frontiersin.org
nuclear translocation of MEF2C, we evaluated the subcellular distribution of MEF2C protein
in cardiac myocytes. … (Figure 2F) revealed that the nuclear-to-cytoplasmic fluorescence ratio …

Hypoxia-induced mitogenic factor promotes cardiac hypertrophy via calcium-dependent and hypoxia-inducible factor-1α mechanisms

S Kumar, G Wang, W Liu, W Ding, M Dong, N Zheng… - …, 2018 - Am Heart Assoc
… CaN–NFAT (calcineurin–nuclear factor of activated T cell) … by reducing cytosolic Ca 2+
concentration with L-type Ca 2+ … effect on intracellular Ca 2+ in cardiomyocytes, we examined …