Cyclic AMP signaling in cardiac myocytes

J Leroy, G Vandecasteele, R Fischmeister - Current Opinion in Physiology, 2018 - Elsevier
… at the nuclear envelope suggests a role in transcriptional … and rodent cardiomyocytes [70,
71], the functional role of PDE1 in … of Ca 2+ signals and cAMP levels in paced cardiomyocytes

TRPC3-Nox2 axis mediates nutritional deficiency-induced cardiomyocyte atrophy

SB Sudi, T Tanaka, S Oda, K Nishiyama, A Nishimura… - Scientific reports, 2019 - nature.com
… the release of stored Ca 2+ 14,15 . Despite being a potent activator of Ca 2+ -dependent
nuclear factor of activated T cells (NFAT), ATP does not induce cardiomyocyte hypertrophy 16,…

TRPC3 regulates the automaticity of embryonic stem cell-derived cardiomyocytes

Z Qi, CK Wong, CH Suen, J Wang, C Long… - International journal of …, 2016 - Elsevier
… Taken together with the finding that TRPC3 positively regulated the LCR, we speculate that
Ca 2 + influx through TRPC3, through increasing the LCR, drives the forward mode of NCX, …

[HTML][HTML] Ca 2+/Calmodulin-dependent kinase II delta B is essential for cardiomyocyte hypertrophy and complement gene expression after LPS and HSP60 stimulation …

CV Cruz Junho, M Trentin-Sonoda, JM Alvim… - Brazilian Journal of …, 2019 - SciELO Brasil
… the nuclear translocation of nuclear factor-kappa B (NF-κB). Despite the importance of
the complement system in CVDs, only a few studies have examined the role of … Ca2+/calmodulin-…

Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart

A Hulikova, KC Park, AA Loonat… - Basic Research in …, 2022 - Springer
… by transcriptomics of neonatal cardiomyocytes cultured over a … We also characterised the
relationship between nuclear and … stimulation at 0.8, 2 or 4 Hz to load Ca 2+ stores. To produce …

… H9c2 cardiomyocytes against oxygen-glucose deprivation/reoxygenation-induced intracellular calcium overload and apoptosis through regulating FKBP12. 6/RyR2 …

M Yuan, XW Meng, J Ma, H Liu, SY Song… - Drug design …, 2019 - Taylor & Francis
… on Ca 2+ signaling and apoptosis in H9c2 cardiomyocytes … differentiation primary response
88-nuclear factor-kappa B via … activation induced Ca 2+ leakage via regulating FKBP12.6 …

Rg3 promotes the SUMOylation of SERCA2a and corrects cardiac dysfunction in heart failure

Z Liu, X Bian, W Gao, J Su, C Ma, X Xiao, T Yu… - Pharmacological …, 2021 - Elsevier
Ca 2+ homeostasis in heart failure has not been reported. In this study, we showed a novel
role of Rg3 in the abnormal Ca 2+ cycle in cardiomyocytes … /nuclear transfer, regulates

TRPC5-eNOS axis negatively regulates ATP-induced cardiomyocyte hypertrophy

C Sunggip, K Shimoda, S Oda, T Tanaka… - Frontiers in …, 2018 - frontiersin.org
… These ligands can induce hypertrophic growth of neonatal rat cardiomyocytes (NRCMs)
mainly through Ca 2+ -dependent calcineurin/nuclear factor of activated T cell (NFAT) signaling …

Hypertrophy of human embryonic stem cell–derived cardiomyocytes supported by positive feedback between Ca2+ and diacylglycerol signals

C Deisl, M Fine, OW Moe, DW Hilgemann - Pflügers Archiv-European …, 2019 - Springer
… Local Ca 2+ signals generated by IP 3 -dependent Ca 2+ release at the nuclear envelope
… That DAG signaling plays a key role in the initiation of hypertrophy is demonstrated, for …

Cardiomyocyte-specific deletion of Orai1 reveals its protective role in angiotensin-II-induced pathological cardiac remodeling

S Segin, M Berlin, C Richter, R Medert, V Flockerzi… - Cells, 2020 - mdpi.com
Ca 2+ signaling in cardiomyocytes. Store-operated calcium entry (SOCE) has been described
in adult and neonatal murine cardiomyocytes… , one through the nuclear factor of activated T …